Results 91 to 100 of about 36,513 (260)

Makarnal ı k Buğdayda Triticum durum Desf. Gama I şini ve EMS'nin Farkl ı Dozları n ı n Klorofil Mutasyonları n ı n Oluşumu Üzerine Etkileri [PDF]

open access: yes, 2002
lslah programlar ı n ı n temel hedefi verimi yüksek makarnal ı k buğday Triticum durum Desf. çeşitlerini geliştirmektir. Islah programlar ı mevcut olan çeşitliliğ i art ı rmay ı ve genetik varyasyonu zenginle ştirmeyi amaçlar.
Mehmet Ali Sakın, Özer Sencar
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Dissociative Bipolar At-Risk Phenotype: Traumatic Burden and Subthreshold Affective Psychopathology in a Help-Seeking Youth Sample

open access: yesBrain Sciences
Background: Youth mental health services increasingly encounter adolescents and young adults with complex affective presentations and trauma histories. Dissociation has been proposed as a clinically relevant marker within bipolar vulnerability pathways ...
Francesca Scopetta   +5 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

The Rotation of Classical Bulges in Barred Galaxies in the Presence of Gas

open access: yesUniverse
Barred galaxies often develop a box/peanut pseudobulge, but they can also host a nearly spherical classical bulge, which is known to gain rotation due to the bar. We aim to explore how the presence of gas impacts the rotation of classical bulges.
Rubens E. G. Machado   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Türkçe meallerde Ashab-ı Kehf ile ilgili yapılan hatalar

open access: yes, 2013
Kur'an'ın dili olan Arapçayı bilmeyenler için ayetlerin ne demek istediğini anlamanın en başta gelen yolu, Kur'an mealierine başvurmaktır. Ülkemizde Kur' an mealieri hiç hız kaybetmeden yazılmaya devam etmektedir.
Durmuş, Zülfikar
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Kamus-ı Teşrih [PDF]

open access: yes, 2018
Kitap1923 basımı olan Kamus-u Teşrih, Osmanlı Türkçesi ile Anatomiye ilişkin terimleri anlatmaya yöneliktir. Diğer alanlara analık eden Anatominin hekimler ve hekim adaylarınca daha iyi anlaşılması çabasının açık biçimde görüldüğü eser, uluslararası ...
Yayın Yönetmeni: Şeker, Muzaffer
core   +1 more source

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