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2020
B cell development and activation are accompanied by dynamic genetic alterations including V(D)J rearrangements and immunoglobulin-gene somatic hypermutation and class-switch recombination. Abnormalities in these genetic events can cause chromosomal translocations and genomic mutations, leading to altered expression and function of genes involved in B ...
Xin, Meng, Qing, Min, Ji-Yang, Wang
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B cell development and activation are accompanied by dynamic genetic alterations including V(D)J rearrangements and immunoglobulin-gene somatic hypermutation and class-switch recombination. Abnormalities in these genetic events can cause chromosomal translocations and genomic mutations, leading to altered expression and function of genes involved in B ...
Xin, Meng, Qing, Min, Ji-Yang, Wang
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Current Treatment Options in Oncology, 2014
The standard frontline therapy for diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and mantle cell lymphoma (MCL) includes the use of chemoimmunotherapy and/or radiation therapy. When patients with these diseases relapse or are refractory to therapy, their diseases are considered incurable outside of the setting of an autologous or ...
Kami, Maddocks, Kristie A, Blum
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The standard frontline therapy for diffuse large B-cell lymphoma (DLBCL), follicular lymphoma (FL), and mantle cell lymphoma (MCL) includes the use of chemoimmunotherapy and/or radiation therapy. When patients with these diseases relapse or are refractory to therapy, their diseases are considered incurable outside of the setting of an autologous or ...
Kami, Maddocks, Kristie A, Blum
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New England Journal of Medicine, 1984
The cells of most tumors are considered to be genetically homogeneous because they are assumed to represent a single clone descended from one abnormal cell. We have discovered three cases of B-cell lymphoma for which this generalization is not true.
J, Sklar +5 more
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The cells of most tumors are considered to be genetically homogeneous because they are assumed to represent a single clone descended from one abnormal cell. We have discovered three cases of B-cell lymphoma for which this generalization is not true.
J, Sklar +5 more
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Human Pathology, 1987
A case of malignant lymphoma probably representing the neoplastic counterpart of "monocytoid B cells" is described. The lymphoma cells had medium-sized, oval to indented nuclei and moderate amounts of pale cytoplasm. Immunohistochemical studies on cryostat sections revealed positive staining for pan-B, B1, B4, BA2, 12 (HLA-DR), and IgM lambda, but not ...
C S, Ng, J K, Chan
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A case of malignant lymphoma probably representing the neoplastic counterpart of "monocytoid B cells" is described. The lymphoma cells had medium-sized, oval to indented nuclei and moderate amounts of pale cytoplasm. Immunohistochemical studies on cryostat sections revealed positive staining for pan-B, B1, B4, BA2, 12 (HLA-DR), and IgM lambda, but not ...
C S, Ng, J K, Chan
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Dermatologic Clinics, 1985
The various morphologic and functional subtypes of nodal B-cell lymphomas can also be found in the skin. These reflect the various steps of lymphocyte differentiation including maturation from the pre-B lymphocyte to the well-differentiated B2 lymphocyte or plasma cell in the peripheral blood.
G, Burg +4 more
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The various morphologic and functional subtypes of nodal B-cell lymphomas can also be found in the skin. These reflect the various steps of lymphocyte differentiation including maturation from the pre-B lymphocyte to the well-differentiated B2 lymphocyte or plasma cell in the peripheral blood.
G, Burg +4 more
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American Journal of Clinical Pathology, 1993
Monocytoid B-cell lymphoma is a distinct clinicopathologic entity occurring primarily in the lymph nodes of elderly patients. Its unique features compared with other low-grade lymphomas are also its characteristic morphologic features. These are its rare leukemic conversion and infrequent bone marrow involvement, and its relatively common association ...
S S, Shin, K, Sheibani
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Monocytoid B-cell lymphoma is a distinct clinicopathologic entity occurring primarily in the lymph nodes of elderly patients. Its unique features compared with other low-grade lymphomas are also its characteristic morphologic features. These are its rare leukemic conversion and infrequent bone marrow involvement, and its relatively common association ...
S S, Shin, K, Sheibani
openaire +2 more sources