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Origin and Pathogenesis of B Cell Lymphomas
2012Immunoglobulin (IG) gene remodeling by V(D)J recombination plays a central role in the generation of normal B cells, and somatic hypermutation and class switching of IG genes are key processes during antigen-driven B cell differentiation. However, errors of these processes are involved in the development of B cell lymphomas.
Seifert, Marc +2 more
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2008
The indolent B-cell lymphomas account for about one third of all lymphomas in the Western world. The follicular lymphomas are the largest and most easily recognized category of indolent lymphoma, representing about one quarter of lymphomas in the Western world.1, 2, 3 The incidence of follicular lymphoma is markedly lower in Asia than in the West, for ...
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The indolent B-cell lymphomas account for about one third of all lymphomas in the Western world. The follicular lymphomas are the largest and most easily recognized category of indolent lymphoma, representing about one quarter of lymphomas in the Western world.1, 2, 3 The incidence of follicular lymphoma is markedly lower in Asia than in the West, for ...
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1992
B-cell lymphomas are tumours of immunocompetent cells, whose function it is to produce Ig. Correspondingly, Ig can be demonstrated in most B-cell lymphomas, either on the surface of tumour cells (slg) or in the cytoplasm (clg). In principle, the demonstration of clg is equivalent to Ig secretion.
Karl Lennert, Alfred Christian Feller
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B-cell lymphomas are tumours of immunocompetent cells, whose function it is to produce Ig. Correspondingly, Ig can be demonstrated in most B-cell lymphomas, either on the surface of tumour cells (slg) or in the cytoplasm (clg). In principle, the demonstration of clg is equivalent to Ig secretion.
Karl Lennert, Alfred Christian Feller
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1987
The classification of malignant lymphoma has always been a controversial subject, well-reflected in Rupert Willis’ statement, “nowhere in pathology has a chaos of names so clouded clear concepts as in the subject of lymphoid tumours” (Willis 1948). Despite the fact that non-Hodgkin’s lymphoma is at least twice as common as Hodgkin’s disease, it is ...
Ian J. Forbes, Anthony S-Y. Leong
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The classification of malignant lymphoma has always been a controversial subject, well-reflected in Rupert Willis’ statement, “nowhere in pathology has a chaos of names so clouded clear concepts as in the subject of lymphoid tumours” (Willis 1948). Despite the fact that non-Hodgkin’s lymphoma is at least twice as common as Hodgkin’s disease, it is ...
Ian J. Forbes, Anthony S-Y. Leong
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2007
The B-cell lymphomas (BCLs) represent 80% to 90% of non-Hodgkin lymphomas in the Western world and include multiple lymphoma subtypes with different biologies, natural histories, morphologic characteristics, immunophenotypes, genetic features, prognoses, and responses to therapy.1 Numerous subtypes of B-cell malignancies are defined according to the ...
Rita M. Braziel, Guang Fan
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The B-cell lymphomas (BCLs) represent 80% to 90% of non-Hodgkin lymphomas in the Western world and include multiple lymphoma subtypes with different biologies, natural histories, morphologic characteristics, immunophenotypes, genetic features, prognoses, and responses to therapy.1 Numerous subtypes of B-cell malignancies are defined according to the ...
Rita M. Braziel, Guang Fan
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Aggressive B-cell Lymphomas: Diffuse Large B-cell Lymphoma and Burkitt Lymphoma
2009This chapter covers aggressive B-cell lymphomas, including diffuse large B-cell lymphoma and its recognized variants, as well as Burkitt lymphoma. Other types of aggressive B-cell tumors, namely acute B-lymphoblastic leukemia and mantle cell lymphoma, are covered in Chaps. 13 and 16, respectively.
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2011
A 70-year-old male presented to his primary care physician complaining of a left neck mass. He was otherwise healthy and asymptomatic. He was referred for fine needle aspiration to further characterize his neck mass. The fine needle aspiration revealed that the mass was an enlarged lymph node with an admixture of small lymphocytes and scattered highly ...
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A 70-year-old male presented to his primary care physician complaining of a left neck mass. He was otherwise healthy and asymptomatic. He was referred for fine needle aspiration to further characterize his neck mass. The fine needle aspiration revealed that the mass was an enlarged lymph node with an admixture of small lymphocytes and scattered highly ...
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Critical Care Management of Chimeric Antigen Receptor T-Cell Therapy Recipients
Ca-A Cancer Journal for Clinicians, 2022Sandrine Valadè +2 more
exaly