Деякі показники гуморального імунітету у дітей з гострою лімфобластною лейкемією під час проведення хіміотерапії та у період довготривалої ремісії [PDF]
Резюме. Досліджено окремі показники гуморального імунітету у 87 дітей з гострим лімфобластним лейкозом (ГЛЛ). Результати досліджень свідчать, що під час програмного лікування з приводу ГЛЛ спостерігається зниження вмісту В-лімфоцитів (CD19+) та ...
Дубей, Л.Я. +8 more
core
ABSTRACT Objective Recurrent high‐grade gliomas have a poor prognosis and limited therapeutic options. This study aimed to evaluate the safety and efficacy of SYHA1813, a dual inhibitor of VEGFR and CSF1R, in patients with recurrent high‐grade gliomas.
Zhuang Kang +16 more
wiley +1 more source
I-REGION GENES ARE EXPRESSED ON T AND B LYMPHOCYTES [PDF]
Peter Lonai, Hugh O. McDevitt
openalex +1 more source
ABSTRACT Objective To quantify the number and volume of whole brain perivascular spaces (PVS) using a detection and segmentation algorithm in participants with multiple sclerosis (MS) and patients with disorders mimicking MS known to potentially influence PVS, such as cerebrovascular disease.
Elle M. Levit +5 more
wiley +1 more source
Endotoxin protein is a mitogen and polyclonal activator of human B lymphocytes. [PDF]
G W Goodman, Barnet M. Sultzer
openalex +1 more source
INF2‐Related Charcot–Marie–Tooth Disease in a Japanese Cohort: Genetic and Clinical Insights
ABSTRACT Background INF2 mutations cause focal segmental glomerulosclerosis (FSGS) and Charcot–Marie–Tooth disease (CMT). Accurate genetic diagnosis is critical, as INF2‐related FSGS is typically resistant to immunotherapy yet rarely recurs after transplantation, and its associated neuropathy can mimic treatable immune‐mediated disorders such as ...
Chikashi Yano +27 more
wiley +1 more source
A Quantitative Study at the Single Cell Level of Immunoglobulin Antigenic Determinants Present on the Surface of Murine B and T Lymphocytes [PDF]
Stratis Avraméas +4 more
openalex +1 more source
Clonal analysis of a human antibody response. Quantitation of precursors of antibody-producing cells and generation and characterization of monoclonal IgM, IgG, and IgA to rabies virus. [PDF]
We quantitated and characterized the changes in the human B cell repertoire, at the clonal level, before and after immunization with rabies virus. Moreover, we generated 10 monoclonal cell lines producing IgM, IgG, and IgA antibodies to the virus.
Casali, P +6 more
core
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich +10 more
wiley +1 more source
Activation of Human B Lymphocytes [PDF]
Barton F. Haynes, Anthony S. Fauci
openalex +1 more source

