Results 181 to 190 of about 779,870 (354)

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

B lymphocytes contribute Angiotensin II induced cardiac hypertrophy. [PDF]

Sci Rep
Zhao X, Di X, Wu H, Fang C, Zhu C, Yue T, Zhang D, Jia H, Zhao J, Liang D, Liu J, Gao X, Hao Y.   +12 more
europepmc   +1 more source

Stress hormones or general well-being are not altered in immune-deficient mice lacking either T- and B- lymphocytes or Interferon gamma signaling if kept under specific pathogen free housing conditions

, 2020
Sarah Jeuthe, Josephine Kemna, C P Kemna, Dario Zocholl, Robert Klopfleisch, Rupert Palme, Clemens Kirschbaum, Christa Thoene-Reineke, Thomas Kammertoens   +8 more
openalex   +2 more sources

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

The Level and Clinical Significance of B Lymphocytes and Immune Molecules (IL-4, IL-10, BAFF, and IgD) in Psoriasis. [PDF]

Immun Inflamm Dis
Wu B, Qin R, Lai L, Li S, Lin R, Zhang Y, Guan Y, Yuan Y.   +7 more
europepmc   +1 more source

An Immunodominant K ^b -Restricted Peptide from the p15E Transmembrane Protein of Endogenous Ecotropic Murine Leukemia Virus (MuLV) AKR623 That Restores Susceptibility of a Tumor Line to Anti-AKR/Gross MuLV Cytotoxic T Lymphocytes [PDF]

, 1994

openalex   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

B Lymphocytes Impede Tregs to Erode Islet Tolerance in Type 1 Diabetes. [PDF]

Diabetes
Wilson CS, Stocks BT, Falk AC, Moore DJ.
europepmc   +1 more source

Adenoviral vectors infect B lymphocytes in vivo. [PDF]

Mol Ther, 2023
Rice-Boucher PJ, Mendonça SA, Alvarez AB, Sturtz AJ, Lorincz R, Dmitriev IP, Kashentseva EA, Lu ZH, Romano R, Selby M, Pingale K, Curiel DT.   +11 more
europepmc   +1 more source

Ewing sarcoma gene EWS is essential for meiosis and B lymphocyte development [PDF]

, 2007
Kai Li, Wendy T. Watford, Cuiling Li, Alissa Parmelee, Mark Bryant, Chuxia Deng, John J. O’Shea, Sean Bong Lee   +7 more
openalex   +1 more source