Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani+4 more
wiley +1 more source
A tumor-infiltrating B lymphocytes -related index based on machine-learning predicts prognosis and immunotherapy response in lung adenocarcinoma. [PDF]
Fang J+8 more
europepmc +1 more source
Immunofluorescent Detection of Human B Cell Alloantigens on S-Ig-Positive Lymphocytes and Epidermal Langerhans Cells [PDF]
Georg Stingl+3 more
openalex +1 more source
Reduced T helper and B lymphocytes in Parkinson's disease
C. Stevens+7 more
semanticscholar +1 more source
This study presents alkylated nitrobenzoselenadiazole (NBSD) photosensitizers that self‐assemble into programmable aggregates, enabling photo‐triggered pyroptosis and enhanced ROS generation. The lead compound, NBSD‐NOc, exhibits superior photodynamic activity, high cellular uptake, and implantable gel compatibility with pH‐responsive release.
Jong Min An+8 more
wiley +1 more source
Citrullinated Autoantigen-Specific T and B Lymphocytes in Rheumatoid Arthritis: Focus on Follicular T Helper Cells and Expansion by Coculture. [PDF]
Ammon T+5 more
europepmc +1 more source
The Role of Macrophages in the Production of Lymphokines by T and B Lymphocytes [PDF]
Sharon M. Wahl+3 more
openalex +1 more source
Multiscale Profiling of Nanoscale Metal‐Organic Framework Biocompatibility and Immune Interactions
A multi‐scale, hierarchical ‘Safety‐by‐Design’ pipeline combining machine learning, ex vivo human blood assays, and in vivo models enables the systematic immunotoxicity and biocompatibility profiling of nanoscale metal‐organic frameworks, accelerating their safe clinical translation. Abstract The clinical translation of metal‐organic frameworks (MOFs) –
Yunhui Zhuang+12 more
wiley +1 more source
Lrba participates in the differentiation of IgA+ B lymphocytes through TGFβR signaling. [PDF]
Flores-Hermenegildo JM+8 more
europepmc +1 more source