Results 191 to 200 of about 412,586 (258)

Some outcomes on b-metric space

Journal of Mathematical and Computational Science, 2020
openaire   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Improvement of magnetic resonance imaging diffusion metric 'slow diffusion coefficient (SDC)' over apparent diffusion coefficient (ADC) for isocitrate dehydrogenase (IDH) genotyping in diffuse gliomas. [PDF]

Quant Imaging Med Surg
Zheng WY, Shi YT, He YY, Lin RL, Xiao BH, Jiang RF, Wáng YXJ.   +6 more
europepmc   +1 more source

On estimating convergence for Pickard sequences in quasi b-metric and rectangular quasi b-metric spaces

In this paper, using the same contractive condition as in [ 3], we give an estimate of the d(xn, x∗) for a sequence {xn} in a quasi b-metric space. In addition, we give another proof for the convergence of a sequence {xn}. Examples of estimation for Banach’s, Kannan’s, and Reich’s fixed point theorems are given.
Bajović, Dušan, Mitrović, Zoran D., Aranđelović, Ivan   +2 more
openaire   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Explicit Applicability Domain Calculations Can Help Determine When Uncertainty Estimates Are Less Reliable. [PDF]

ACS Omega
Hosni Z, Gillet VJ, Marchese Robinson RL.   +2 more
europepmc   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Influence of iris color on corneal densitometry. [PDF]

J Optom
Arizcuren AR, Consejo A.
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Validating Physiologically-Based Pharmacokinetic Models Using the Continuous Ranked Probability Score: Beyond Being Correct on Average. [PDF]

CPT Pharmacometrics Syst Pharmacol
Sluijterman L, van Borselen M, Greupink R, IntHout J.   +3 more
europepmc   +1 more source