Results 131 to 140 of about 456,257 (299)

Space filling with metric measure spaces [PDF]

, 2012
We show a sharp relationship between the existence of space filling mappings with an upper gradient in a Lorentz space and the Poincaré inequality in a general metric setting.
Zürcher, T., Wildrick, K.
core   +1 more source

Some Characteristics of Completeness Property in Fuzzy Soft b−Metric Space

Journal of Applied Science and Engineering
In this study, we developed a novel idea known as the fuzzy soft b-metric, and investigated some fundamental aspects of fuzzy soft b-metric. Moreover, various topological features of this new space, such as fuzzy soft open ball, and fuzzy soft Hausdorff ...
Salim Dawood Mohsen, Younes Hazem Thiyab
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Some Extensions of Fixed Point Results over Quasi-JS-Spaces

Journal of Function Spaces, 2016
We introduce the notion of quasi-JS-metric space. After defining the basic topological properties of quasi-JS-metric space, we investigate fixed point of certain mapping in the frame of complete quasi-JS-metric space.
Maha Noorwali, Hamed H. Alsulami, Erdal Karapınar   +2 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Fixed Point of Interpolative Rus-Reich-Ciric Contraction Mapping on Rectangular Quasi-Partial b-Metric Space

, 2020
[EN] The purpose of this study is to introduce a new type of extended metric space, i.e., the rectangular quasi-partial b-metric space, which means a relaxation of the symmetry requirement of metric spaces, by including a real number s in the definition ...
Swapnil Verma, Gautam, Pragati, Pragati Gautam, Verma, Swapnil, Sánchez Ruiz, Luis Manuel, Luis Manuel Sánchez Ruiz   +5 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Uniform Continuity and a New Bornology for a Metric Space

, 2017
In the context of functions between metric spaces, continuity is preserved by uniform convergence on the bornology of relatively compact subsets while Cauchy continuity is preserved under uniform convergence on the bornology of totally bounded subsets ...
M. Isabel Garrido, Gerald Beer, Beer, Gerald, Ana S. Meroño, Meroño Moreno, Ana Soledad, Garrido Carballo, María Isabel   +5 more
core   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source