Results 111 to 120 of about 173,734 (262)
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Fixed point theorems for nonlinear contractive mappings in ordered b-metric space with auxiliary function. [PDF]
Seshagiri Rao N, Kalyani K, Mitiku B.
europepmc +1 more source
Some results of coincidence points on $b$-metric space
In this paper, we extend some results of a coincidence point for mappings $\psi$, $\varphi$ acting from a metric space to another one — to a space with a generalized distance. In our case, mappings $\psi$, $\varphi$ are acting from $b$-metric space to a space with a generalized distance (distance satisfying only the axiom of identity, i.e., symmetry ...
N. Khial, W. Merchela, S. Benarab
openaire +1 more source
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Statistical Convergence on b-Metric Spaces
This paper investigates the idea of statistical convergence in the context of $b$-metric spaces. As a generalization of classical metric spaces, $b$-metric spaces offer a useful structure to examine the basic concepts of statistical convergence. The results indicate that b-metric spaces provide an impressive theoretical basis for both convergence ...
openaire +2 more sources
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
COINCIDENCE POINT IN B-METRIC SPACE
On the pattern of most classical Banach contraction theorem, now the mathematicians are using Jungck contraction theorem. In this paper I Introduced Jungck contraction and Jungck contraction theorem and using to it I proved coincidences point theorem in b-metric ...
openaire +1 more source

