Results 91 to 100 of about 16,310,261 (292)

Admissible Hybrid Z-Contractions in b-Metric Spaces [PDF]

open access: yesAxioms, 2019
In this manuscript, we introduce a new notion, admissible hybrid Z -contraction that unifies several nonlinear and linear contractions in the set-up of a b-metric space. In our main theorem, we discuss the existence and uniqueness result of such mappings in the context of complete b-metric space.
Ioan Cristian Chifu, Erdal Karapinar
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The B-completion of a T0-quasi-metric space [PDF]

open access: yes, 2009
We continue our study of the conjugate invariant method for completing an arbitrary T0-quasi-metric space which we have introduced in an earlier article under the name of the B-completion.
Kivuvu, Charly Makitu   +1 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

STUDY ABOUT CYCLIC MAP ON PARTIAL b – METRIC SPACES AND FIXED-POINT THEOREM

open access: yesTikrit Journal of Pure Science, 2018
In this paper, we study the existence and uniqueness of fixed point of cyclic map α-admissible on partial b – metric ...
Muayyad Mahmood Khalil
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Some ϕ-fixed point results in b-metric spaces with applications

open access: yesCumhuriyet Science Journal, 2019
The fixed point theory is the most important topic in mathematics anaysis. This topic has many applications in the different fields. It demonstrates the uniqueness of the existence of a mapping and how it can be found.
Müzeyyen Sangurlu Sezen
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy