Results 81 to 90 of about 456,257 (299)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

TITIK-ANTARA DI DALAM RUANG METRIK DAN RUANG INTERVAL METRIK

Barekeng, 2007
A point p in metric space ()dX, is called a between-point of if Xba∈,()()(bpdpadbad,,,+= ). This concept was formulated by Menger in 1928. If all the between-points of a and b is collected in a set, then a and b are that set automaticlly. In the metric
Mozart W. Talakua
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

On Topology of Fuzzy Strong b-Metric Spaces

Journal of New Theory, 2018
In this study, we introduce and investigate the concept of fuzzy strong b-metric space such that is a fuzzy analogy of strong b-metric spaces. By using the open balls, we define a topology on these spaces which is Hausdor® and first countable. Later
Tarkan Oner
doaj  

Fixed point theorems in complex valued b-metric spaces [PDF]

Mathematica Moravica, 2023
In this paper, we have proved common fixed point theorems using Hardy and Rogers type contraction condition in complex-valued b-metric spaces The results of the paper extend the results proved in S. Ali [1].
Barman Dinanath, Sarkar Krishnadhan, Tiwary Kalishankar   +2 more
doaj  

Some results in quasi-b-metric-like spaces [PDF]

Journal of Inequalities and Applications, 2014
Abstract In this paper, we introduce a new concept of quasi-b-metric-like spaces as a generalization of b-metric-like spaces and quasi-metric-like spaces. Some fixed point theorems are investigated in quasi-b-metric-like spaces. Moreover, an example is given to support one of our results. MSC:47H10, 54H25.
Zhu, Chuanxi, Chen, Chunfang, Zhang, Xiaozhi   +2 more
openaire   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Some fixed point theorems for contractive multivalued mappings in Menger probabilistic metric like spaces

پژوهش‌های ریاضی, 2021
In this paper,  first by using the constructions of probabilistic b-metric Menger space and probabilistic metric like Menger space,  we introduce probabilistic b-metric like Menger space and present some examples of it.
Mahnaz Khanehgir, Reza Allahyari
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Reaction Networks and the Metric Structure of Chemical Space(s)

, 2019
In this paper, we develop a formal definition of chemical space as a discrete metric space of molecules and analyze its properties. To this end, we utilize the shortest path metric on reaction networks to define a distance function between molecules of ...
Dmitrij Rappoport (1273044), Dmitrij, Rappoport, Dmitrij Rappoport (5436785)   +2 more
core   +1 more source