Results 81 to 90 of about 173,734 (262)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

A Unification of G-Metric, Partial Metric, and b-Metric Spaces

open access: yesAbstract and Applied Analysis, 2014
Using the concepts of G-metric, partial metric, and b-metric spaces, we define a new concept of generalized partial b-metric space. Topological and structural properties of the new space are investigated and certain fixed point theorems for contractive ...
Nawab Hussain   +3 more
doaj   +1 more source

Controlled Metric Type Spaces and the Related Contraction Principle

open access: yesMathematics, 2018
In this article, we introduce a new extension of b-metric spaces, called controlled metric type spaces, by employing a control function α ( x , y ) of the right-hand side of the b-triangle inequality.
Nabil Mlaiki   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Some ϕ-fixed point results in b-metric spaces with applications

open access: yesCumhuriyet Science Journal, 2019
The fixed point theory is the most important topic in mathematics anaysis. This topic has many applications in the different fields. It demonstrates the uniqueness of the existence of a mapping and how it can be found.
Müzeyyen Sangurlu Sezen
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Stone-type theorem on b-metric spaces and applications

open access: yesTopology and its Applications, 2015
A triple \((X,d,k)\) is called a \(b\)-metric space if \(X\) is a non-empty set, \(k\geq 1\) is a constant, and \(d: X\times X\to[0,+\infty)\) is a function satisfying (1) \(d(x,y)= 0\) if and only if \(x=y\), (2) \(d(x,y)= d(y, x)\), and (3) \(d(x, z)\leq k[d(x,y)+ d(y, z)]\) for all \(x,y,z\in X\). For \(k=2\), \(b\)-metric spaces were introduced by \
Tran Van An   +2 more
openaire   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Fuzzy Cone B-Metric Spaces

open access: yes, 2019
The first two authors would like to thank TUBITAK (The Scientific and Technological Research Council of Turkey) for its financial support during their doctorate studies.
POŞUL, Hande   +2 more
openaire   +3 more sources

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