Results 71 to 80 of about 16,310,261 (292)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Duality and quasi-normability for complexity spaces

open access: yesApplied General Topology, 2002
The complexity (quasi-metric) space was introduced in [23] to study complexity analysis of programs. Recently, it was introduced in [22] the dual complexity (quasi-metric) space, as a subspace of the function space [0,) ω. Several quasi-metric properties
Salvador Romaguera, M.P. Schellekens
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

A cohomological characterisation of Yu's Property A for metric spaces

open access: yes, 2012
We introduce the notion of an asymptotically invariant mean as a coarse averaging operator for a metric space and show that the existence of such an operator is equivalent to Yu’s property A.
Wright, Nick   +2 more
core   +1 more source

Almost Contact B-metric Manifoldsas Extensions of a 2-dimensional Space-form [PDF]

open access: yes, 2016
summary:The object of investigations are almost contact B-metric manifolds which are derived as a product of a real line and a 2-dimensional manifold equipped with a complex structure and a Norden metric.
Manev, Hristo M.
core   +1 more source

Fixed point theorems in complex valued b-metric spaces [PDF]

open access: yesMathematica Moravica, 2023
In this paper, we have proved common fixed point theorems using Hardy and Rogers type contraction condition in complex-valued b-metric spaces The results of the paper extend the results proved in S. Ali [1].
Barman Dinanath   +2 more
doaj  

Fixed point theorems for generalized ( α , ψ ) $(\alpha ,\psi )$ -contraction mappings in rectangular quasi b-metric spaces

open access: yesFixed Point Theory and Algorithms for Sciences and Engineering, 2022
In this paper, we introduce the class of rectangular quasi b-metric spaces as a generalization of rectangular metric spaces, rectangular quasi-metric spaces, rectangular b-metric spaces, define generalized ( α , ψ ) $(\alpha ,\psi ) $ -contraction ...
Bontu Nasir Abagaro   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Reaction Networks and the Metric Structure of Chemical Space(s) [PDF]

open access: yes, 2019
In this paper, we develop a formal definition of chemical space as a discrete metric space of molecules and analyze its properties. To this end, we utilize the shortest path metric on reaction networks to define a distance function between molecules of ...
Dmitrij Rappoport (1273044)   +2 more
core   +1 more source

Weak Partial b-Metric Spaces and Nadler’s Theorem

open access: yesMathematics, 2019
The purpose of this paper is to define the notions of weak partial b-metric spaces and weak partial Hausdorff b-metric spaces along with the topology of weak partial b-metric space. Moreover, we present a generalization of Nadler’s theorem by using
Tanzeela Kanwal   +3 more
doaj   +1 more source

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