Results 71 to 80 of about 1,274,301 (280)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
A note on convex renorming and fragmentability
, 2005 Using the game approach to fragmentability, we give new and simpler proofs of the following known results: (a) If the Banach space admits an equivalent Kadec norm, then its weak topology is fragmented by a metric which is stronger than the norm topology.
Mirmostafaee, A K
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Integral Operators in b-Metric and Generalized b-Metric Spaces and Boundary Value Problems
Fractal and FractionalWe study fixed-point theorems of contractive mappings in b-metric space, cone b-metric space, and the newly introduced extended b-metric space. To generalize an existence and uniqueness result for the so-called Φs functions in the b-metric space to the ...
Christopher Middlebrook, Wenying Feng
doaj +1 more source
Fractal and Fractional, 2023 This manuscript contains several new notions including intuitionistic fuzzy Nb metric space, intuitionistic fuzzy quasi-Sb-metric space, intuitionistic fuzzy pseudo-Sb-metric space, intuitionistic fuzzy quasi-N-metric space and intuitionistic fuzzy ...
Umar Ishtiaq +5 more
doaj +1 more source
M-convex structure on b-metric spaces
Filomat, 2021 We apply the concept of a m-convex b-metric space by introducing of m-convex structure on b-metric spaces. We obtain fixed point theorems in this structure. Recent results are concluded in our targets, as well. Some illustrated examples are presented to confirm our main results.
Gholamhossein Amirbostaghi +2 more
openaire +2 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Fixed Point Theory and Applications, 2019 In this paper, we introduce the structure of Sp $S_{p}$-metric spaces as a generalization of both S-metric and Sb $S_{b}$-metric spaces. Also, we present the notions of S̃-contractive mappings in the setup of ordered Sp $S_{p}$-metric spaces and ...
Z. Mustafa +4 more
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
On Ciric type theorems in b-metric spaces
Publications de l'Institut Mathematique, 2023 We show that the range of contraction constant in a result of Karap?nar et al. can not be extended to [0, 1). However, by using some additional conditions, we prove that the range can be extended to [0,1). The first result gives a negative answer to the open question on a Ciric type theorem in b-metric spaces, and the next results are ...
openaire +2 more sources