Results 91 to 100 of about 104,464 (301)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

On R-Partial b-Metric Spaces and Related Fixed Point Results with Applications

open access: yesJournal of Function Spaces, 2020
In this paper, we introduce the notion of R-partial b-metric spaces and prove some related fixed point results in the context of this notion. We also discuss an example to validate our result.
Muhammad Usman Ali   +5 more
doaj   +1 more source

Convexity in quasi-metric spaces

open access: yes, 2012
Includes abstract.Includes bibliographical references.The principal aim of this thesis is to investigate the existence of an injective hull in the categories of T-quasi-metric spaces and of T-ultra-quasi-metric spaces with nonexpansive ...
Otafudu, Olivier Olela
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Hyperconvexity and endpoints in T₀-quasi-metric spaces

open access: yes, 2013
Over the last decades much progress has been made in the investigation of hyperconvexity in metric spaces. Recently Kemajou and others have published an article concerning hyperconvexity in T₀-quasi-metric spaces.
Haihambo, Paulus
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Controlled Metric Type Spaces and the Related Contraction Principle

open access: yesMathematics, 2018
In this article, we introduce a new extension of b-metric spaces, called controlled metric type spaces, by employing a control function α ( x , y ) of the right-hand side of the b-triangle inequality.
Nabil Mlaiki   +3 more
doaj   +1 more source

A representation theorem for probabilistic metric spaces in general [PDF]

open access: yes, 1978
summary:In this paper, we present a representation theorem for probabilistic metric spaces in ...
Nagata, J., Morrel, B., Liu, Mingxue
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Notes on separability in metric sets [PDF]

open access: yes
These notes consider the various topologies over metric sets generated by a selection of the metric axioms given below.
Matthews, Stephen G.
core  

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