Results 61 to 70 of about 45,072 (266)

Generalized Cardinal Polishing Splines Signal Reconstruction

open access: yesMathematics
Sampling and reconstruction are indispensable processes in signal processing, and appropriate foundations are crucial for spline reconstruction models.
Fangli Sun, Zhanchuan Cai
doaj   +1 more source

Physics‐Informed Neural Network‐Enabled Forward Prediction and Inverse Design of Ring Origami

open access: yesAdvanced Science, EarlyView.
This work presents a KRT‐PINN framework that integrates Kirchhoff rod theory with physics‐informed neural networks for the forward prediction and inverse design of ring origami consisting of closed‐loop rods. The framework predicts stable states of segmented rings with prescribed natural‐curvature profiles and determines the natural‐curvature profiles ...
Luyuan Ning   +3 more
wiley   +1 more source

Use of Smoothing Methods for Estimating the Coefficients of Time Dependent Rate Models in Survival Analysis and its Application in Psoriasis Disease

open access: yesمجله اپیدمیولوژی ایران, 2016
Background and Objectives: In studies in which each person may experience an event at different times, they are recurrent events.One of the most popular approaches in analyzing recurrent event is obtaining an estimate of the means/rate of events at ...
F Osmani, E Hajizadeh, P Mansoori
doaj  

B-splines on the Heisenberg Group

open access: yesComplex Analysis and Operator Theory
Abstract The aim of this paper is to introduce a class of B-splines $${\phi }_n$$ ϕ n on the Heisenberg group $${\mathbb {H}}$$
Das, S. R., Massopust, P., Radha, R.
openaire   +3 more sources

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

open access: yesAdvanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer   +9 more
wiley   +1 more source

CALIBRATION RELATIONS FOR ANALOGUES OF THE BASIS SPLINES WITH UNIFORM NODES

open access: yesUral Mathematical Journal, 2017
The paper deals with generalized linear and parabolic B-splines with the uniform nodes constructed by means only one function \(\varphi(x)\). For such splines in this paper conditions have been found that guarantee satisfaction of two-scale relations.
Valerii T. Shevaldin
doaj   +1 more source

A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance

open access: yesAdvanced Science, EarlyView.
Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng   +12 more
wiley   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

open access: yesAdvanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie   +12 more
wiley   +1 more source

EndoTac: An Endoscopic Camera‐Based Tactile Sensor with High Sensitivity for Minimally Invasive Surgery

open access: yesAdvanced Science, EarlyView.
EndoTac presents a trocar‐compatible endoscopic vision‐based tactile sensor that uses a convex mirror to enlarge side‐facing tactile coverage during minimally invasive vessel palpation. Distorted tactile images are unwarped and processed by a learning model to estimate vascular deformation, enabling sensitive, spatially distributed tactile perception ...
Yupeng Wang   +5 more
wiley   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

open access: yesAdvanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni   +17 more
wiley   +1 more source

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