Results 161 to 170 of about 5,411,122 (304)

Comparing multi-b-value diffusion models and ROI delineation strategies for prediction of p53 abnormality and microsatellite instability in endometrial cancer. [PDF]

BMC Med Imaging
Li Y, Wang X, Xue K, Mao Y, Wang W, Liu X, Wang W, Zhang M.   +7 more
europepmc   +1 more source

Test-retest repeatability of ADC in prostate using the multi b-Value VERDICT acquisition. [PDF]

Eur J Radiol, 2023
Rogers HJ, Singh S, Barnes A, Obuchowski NA, Margolis DJ, Malyarenko DI, Chenevert TL, Shukla-Dave A, Boss MA, Punwani S.   +9 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Differentiating Brain Metastasis and High-Grade Glioma Using Multi-b Value Diffusion MRI and Tumor Volumetry. [PDF]

J Neuroimaging
Kopřivová T, Dostál M, Jůza T, Vybíhal V, Ovesná P, Kozubek M, Keřkovský M.   +6 more
europepmc   +1 more source

Image quality assessment using deep learning in high b-value diffusion-weighted breast MRI. [PDF]

Sci Rep, 2023
Kapsner LA, Balbach EL, Folle L, Laun FB, Nagel AM, Liebert A, Emons J, Ohlmeyer S, Uder M, Wenkel E, Bickelhaupt S.   +10 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Enhancing prostate cancer detection: The role of b-value and apparent diffusion coefficient in DWI. [PDF]

F1000Res
Goveas B, Dkhar W, Kadavigere R, Nayak K, Pradhan A, Venugopal A, Shastry P, Barnes Abraham N.   +7 more
europepmc   +1 more source

Accelerating High b-Value Diffusion-Weighted MRI Using a Convolutional Recurrent Neural Network (CRNN-DWI). [PDF]

Bioengineering (Basel), 2023
Zhong Z, Ryu K, Mao J, Sun K, Dan G, Vasanawala SS, Zhou XJ.   +6 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

"b value" of diffusion weighted imaging

Tuberkuloz ve Toraks, 2015
openaire   +2 more sources