Results 181 to 190 of about 24,435,209 (289)

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Comparing multi-b-value diffusion models and ROI delineation strategies for prediction of p53 abnormality and microsatellite instability in endometrial cancer. [PDF]

BMC Med Imaging
Li Y, Wang X, Xue K, Mao Y, Wang W, Liu X, Wang W, Zhang M.   +7 more
europepmc   +1 more source

Spatial mapping of b-value and fractal dimension prior to November 8, 2022 Doti Earthquake, Nepal. [PDF]

PLoS One, 2023
Tiwari RK, Paudyal H.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Differentiating Brain Metastasis and High-Grade Glioma Using Multi-b Value Diffusion MRI and Tumor Volumetry. [PDF]

J Neuroimaging
Kopřivová T, Dostál M, Jůza T, Vybíhal V, Ovesná P, Kozubek M, Keřkovský M.   +6 more
europepmc   +1 more source

Test-retest repeatability of ADC in prostate using the multi b-Value VERDICT acquisition. [PDF]

Eur J Radiol, 2023
Rogers HJ, Singh S, Barnes A, Obuchowski NA, Margolis DJ, Malyarenko DI, Chenevert TL, Shukla-Dave A, Boss MA, Punwani S.   +9 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A prospective comparison of the diagnostic performance of a high b-value diffusion-weighted image-guided score versus PI-RADS v2.1 for transition zone prostate cancer. [PDF]

Front Oncol
Li K, Xu T, Yan X, Mi S, Jiang M, Chen L, Kuang F.   +6 more
europepmc   +1 more source

Image quality assessment using deep learning in high b-value diffusion-weighted breast MRI. [PDF]

Sci Rep, 2023
Kapsner LA, Balbach EL, Folle L, Laun FB, Nagel AM, Liebert A, Emons J, Ohlmeyer S, Uder M, Wenkel E, Bickelhaupt S.   +10 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source