Results 171 to 180 of about 24,435,209 (289)

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

Impact of Free Water Correction on the Mean Diffusivity of Glioblastoma is Regional and b-value Dependent: A Retrospective Study on Open-source Datasets. [PDF]

open access: yesMagn Reson Med Sci
Matsushita S   +9 more
europepmc   +1 more source

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Statistical analysis of macromolecular B values

open access: yes11-ая Международная конференция по биоинформатике регуляции и структуры геномов и системной биологии, 2018
Rafiga Masmaliyeva, Garib N Murshudov
openaire   +2 more sources

Estimation of multicomponent flow in the kidney with multi-b-value spectral diffusion. [PDF]

open access: yesMagn Reson Med
Liu MM   +14 more
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Detecting early kidney allograft fibrosis with multi-b-value spectral diffusion MRI. [PDF]

open access: yesSci Rep
Liu MM   +16 more
europepmc   +1 more source

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