Results 191 to 200 of about 30,612,164 (294)

Characterizing the spatial patterns and determinants of cerebrospinal fluid pseudorandom flow in the human brain with low b-value diffusion MRI. [PDF]

Imaging Neurosci (Camb)
Nazeri A, Hosseini H, Dehkharghanian T, Lindsay KE, LaMontagne P, Shimony JS, Benzinger TLS, Sotiras A.   +7 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Standard b-value DWI-derived stiffness index analysis may provide a way to evaluate the development of intracerebral hematoma. [PDF]

Front Neurol
Li Q, Mao J, Wang Q, Yao L, Xu F, Dong F.   +5 more
europepmc   +1 more source

HIgh b‐value and high Resolution Integrated Diffusion (HIBRID) imaging

NeuroImage, 2017
Q. Fan, A. Nummenmaa, J. Polimeni, T. Witzel, S. Huang, V. Wedeen, B. Rosen, L. Wald   +7 more
semanticscholar   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Use of a b-Value of 3000 s/mm² to Differentiate Benign from Malignant Hepatic Masses in Liver Diffusion-Weighted Imaging Using a 3T MR Scanner with a Peak Gradient of 100 mT/m. [PDF]

Juntendo Med J
Sano K, Fukushima K, Machida H, Kariyasu T, Kusahara H, Takahashi S, Nakanishi A, Yokoyama K.   +7 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Study on Acoustic Emission <i>b</i>‑Value Characteristics in Hydraulically Fractured Shale Fracture Propagation under High Confining Pressure Conditions. [PDF]

ACS Omega
Zhao H, Sun W, Liang B, Yang Y, Wang C, Liu Q, Liao B, Bu Y, Zhao Y, Gao Y, Wu X, Zeng X.   +11 more
europepmc   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Comparison of synthesized and acquired high b-value diffusion-weighted MRI for detection of prostate cancer. [PDF]

Cancer Imaging
Kallis K, Conlin CC, Zhong AY, Hussain TS, Chatterjee A, Karczmar GS, Rakow-Penner R, Dale AM, Seibert TM.   +8 more
europepmc   +1 more source