Results 81 to 90 of about 37,865 (209)

Brucella abortus invasion of osteocytes modulates connexin 43 and integrin expression and induces osteoclastogenesis via receptor activator of NF-κB ligand and tumor necrosis factor alpha secretion [PDF]

, 2015
Osteoarticular brucellosis is the most common localization of human active disease. Osteocytes are the most abundant cells of bone. They secrete factors that regulate the differentiation of both osteoblasts and osteoclasts during bone remodeling. The aim
Geyik MF, Hibbs MS, Kato Y, Keenan JD, Kotake S, Lu M, Madkour MM, Young EJ   +7 more
core   +2 more sources

Seroprevalence and Associated Factors of Camel and Human Brucellosis in Dire District, Southern Ethiopia: A One‐Health Perspective

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
The prevalence of camel brucellosis was 4.36%. Being adult, female and large herds were significant risk factors for camel brucellosis. The prevalence of human brucellosis was 3.08%. The presence of a positive animal in the household and camel farmers who consume raw milk were significant factors for human brucellosis.
Yihenew Getahun Ambaw, Diba Guyo Kosi, Shimelis Mengistu, Simegnew Adugna Kallu   +3 more
wiley   +1 more source

Identifikasi Brucella abortus Isolat Lokal dengan Brucella abortus Strain Specific-Polymerase Chain Reaction (IDENTIFICATION OF LOCAL ISOLATES OF BRUCELLA ABORTUS USING BRUCELLA ABORTUS STRAIN SPECIFIC-POLYMERASE CHAIN REACTION ASSAY)

Jurnal Veteriner, 2014
Brucella abortus Strain Specific-Polymerase Chain Reaction (BaSS-PCR) is a single multiplex PCRtechnique which able to identify and differentiate between Brucella abortus field strains (biovar 1, 2, and4), B.
Susan Maphilindawati Noor, Pratiwi Pujilestari Sudarmono, Asmarani Kusumawati, Anis Karuniawati   +3 more
doaj  

B. abortus RNA is the component involved in the down-modulation of MHC-I expression on human monocytes via TLR8 and the EGFR pathway. [PDF]

PLoS Pathogens, 2017
Despite eliciting a potent CD8+ T cell response, Brucella abortus is able to persist and establish a chronic infection inside its host. We have previously reported that the infection of human monocytes/macrophages with B.
M Ayelén Milillo, Lis N Velásquez, Aldana Trotta, M Victoria Delpino, Fábio V Marinho, Luciana Balboa, Mónica Vermeulen, Sonia L Espindola, Nahuel Rodriguez-Rodrigues, Gabriela C Fernández, Sergio Costa Oliveira, Guillermo H Giambartolomei, Paula Barrionuevo   +12 more
doaj   +1 more source

Seroprevalence and Associated Risk Factors of Brucellosis in Backyard Dairy Cattle in the Western Buffer Zone of Chitwan National Park, Nepal

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
A 1.56% prevalence of Brucella abortus antibodies was detected by Ab‐ELISA in backyard dairy cattle in Chitwan, Nepal. Risk factors were not significantly associated with infection, and untested wildlife reservoirs were identified. These findings highlight the need for more systematic, comprehensive studies.
Susan Pyakurel, Sikesh Manandhar, Suhel K. C., Chet Narayan Gyawali, Pragya Koirala   +4 more
wiley   +1 more source

Immunophenotyping of blood cells of experimental animals immunized with Brucella abortus thermoextracts

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Aim. To study the subpopulational structure of blood cells of the experimental animals immunized with thermoextracts (TE) of Brucella abortus in L- and S-form. Materials and methods. Total 100 certified («Vector», Novosibirsk) outbred mice were immunized
S. V. Balakhonov, V. I. Dubrovina, V. V. Voitkova, K. M. Korytov, N. L. Barannikova, V. B. Nikolaev, T. T. Shkaruba   +6 more
doaj   +1 more source

CRISPR‐Cas9‐Generated TXNDC15 c.560delA Homozygous Mouse Model Exhibits Meckel–Gruber Syndrome Phenotype

genesis, Volume 64, Issue 1, February 2026.
ABSTRACT To determine whether TXNDC15 variation causes Meckel–Gruber syndrome (MKS), we assessed the pathogenicity of the frameshift variant c.560delA. A CRISPR–Cas9 generated mouse model carrying the equivalent Txndc15 c.512delA mutation was analyzed at embryonic day 15.5.
Yang Liu, Hui Wang, Liyuan Chen, Xiaoxia Wu, Zhiyong Xu, Qingfa Huang, Hu Zhang, Xiushu Cao, Xinyuan Liang, Xingjian Zhong, Caiqun Luo   +10 more
wiley   +1 more source

The role of T cell subsets and cytokines in the regulation of intracellular bacterial infection [PDF]

, 1998
Cellular immune responses are a critical part of the host's defense against intracellular bacterial infections. Immunity to Brucella abortus crucially depends on antigen-specific T cell-mediated activation of macrophages, which are the major effectors of
Bocca, Anamélia Lorenzetti, Goes, A. M., Harms, J. S., Oliveira, S. C., Rech, E. L., Rodarte, Renato Santos, Splitter, G. A.   +6 more
core   +1 more source

Bacterial RNA Contributes to the Down-Modulation of MHC-II Expression on Monocytes/Macrophages Diminishing CD4+ T Cell Responses

Frontiers in Immunology, 2019
Brucella abortus, the causative agent of brucellosis, displays many resources to evade T cell responses conducive to persist inside the host. Our laboratory has previously showed that infection of human monocytes with B.
M. Ayelén Milillo, Aldana Trotta, Agustina Serafino, José Luis Marin Franco, Fábio V. Marinho, Julieta Alcain, Melanie Genoula, Luciana Balboa, Sergio Costa Oliveira, Guillermo H. Giambartolomei, Paula Barrionuevo   +10 more
doaj   +1 more source

Immunogenicity and protective effect of recombinant Brucella abortus Ndk (rNdk) against a virulent strain B. abortus 544 infection in BALB/c mice [PDF]

FEMS Microbiology Letters, 2015
In this study, we particularly evaluated the protective effect of recombinant protein encoded by Brucella abortus 544 ndk (nucleoside diphosphate kinase) gene against B. abortus infection in the BALB/c mice. Cloning and expression of B. abortus Ndk was accomplished by PCR amplification into a pMAL expression system, and purification of a recombinant ...
Huynh Tan, Hop, Hannah Leah, Simborio, Alisha Wehdnesday Bernardo, Reyes, Lauren Togonon, Arayan, WonGi, Min, Hu Jang, Lee, Dong Hee, Kim, Hong Hee, Chang, Suk, Kim   +8 more
openaire   +2 more sources