Using animal models to disentangle the role of genetic, epigenetic and environmental influences on behavioral outcomes associated with maternal anxiety and depression [PDF]
Frontiers in Psychiatry, 2011 The etiology of complex psychiatric disorders results from both genetics and the environment. No definitive environmental factor has been implicated, but studies suggest that deficits in maternal care and bonding may be an important contributing factor ...
Lisa M. Tarantino +3 more
doaj +2 more sources
Фармакокинетика и ФармакодинамикаRelevance. Cyclo-L-prolylglycine (CPG), discovered as an endogenous compound in the central nervous system, is involved in the formation of a reaction to emotional stress in rodents with a pronounced fear reaction and has an analgesic effect in vivo ...
A. V. Nadorova +3 more
doaj +2 more sources
Optimized cesarean techniques, IVF use, and foster strain selection enhance germ-free mouse production efficiency. [PDF]
Sci RepThis study aims to refine sterile cesarean section techniques, in vitro fertilization (IVF) and foster mother selection strategies to enhance the efficiency of germ-free (GF) mouse production.
Yang Y +5 more
europepmc +2 more sources
Frontiers in Cellular and Infection Microbiology, 2021 Mycoplasma pneumoniae (Mp) is a highly contagious respiratory pathogen responsible for human community-acquired pneumonia. The number of antibiotic-resistant Mp strains is increasing; therefore, to develop novel therapeutics, it is crucial to precisely ...
Shigeyuki Tamiya +11 more
doaj +1 more source
Catheter colonization and abscess formation due to Staphylococcus epidermidis with normal and small-colony-variant phenotype is mouse strain dependent. [PDF]
PLoS ONE, 2012 Coagulase-negative staphylococci (CoNS) form a thick, multilayered biofilm on foreign bodies and are a major cause of nosocomial implant-associated infections.
Gunnar Sander +5 more
doaj +1 more source
Vaccines, 2021 TFPR1 is a novel adjuvant for protein and peptide antigens, which has been demonstrated in BALB/c mice in our previous studies; however, its adjuvanticity in mice with different genetic backgrounds remains unknown, and its adjuvanticity needs to be ...
Qiao Li +7 more
doaj +1 more source
Susceptibility to SARS-CoV-2 Virus Variants of Concern in Mouse Models
Проблемы особо опасных инфекций, 2022 The aim of the research was to assess the susceptibility of mice of different lines to newly emerging variants of SARS-CoV-2.Materials and methods. The SARS-CoV-2 virus strains belonging to variants of concern (VOC) circulating in the territory of the ...
A. V. Shipovalov +9 more
doaj +1 more source
Innate immune basis for rift valley fever susceptibility in mouse models [PDF]
, 2017 Rift Valley fever virus (RVFV) leads to varied clinical manifestations in animals and in humans that range from moderate fever to fatal illness, suggesting that host immune responses are important determinants of the disease severity. We investigated the
Bruhns, Pierre +7 more
core +9 more sources
Frontiers in Immunology, 2017 One of the most common genetic backgrounds for mice used as a model to investigate human diseases is the inbred BALB/c strain. This work is aimed to characterize the pattern of natural anti-carbohydrate antibodies present in the serum of 20 BALB/c mice ...
Daniel Bello-Gil +5 more
doaj +1 more source
Corticotropin-releasing factor receptors couple to multiple g-proteins to activate diverse intracellular signaling pathways in mouse hippocampus: role in neuronal excitability and associative learning [PDF]
, 2003 Corticotropin-releasing factor (CRF) exerts a key neuroregulatory control on stress responses in various regions of the mammalian brain, including the hippocampus.
Blank, T. (Thomas) +5 more
core +2 more sources