Results 1 to 10 of about 81,267 (135)

Murine T Cell-Dependent Response Affects Leishmania amazonensis Amastigote Survival and Virulence. [PDF]

Cell Biol Int
ABSTRACT Our group has previously described the infection course of Leishmania amazonensis in BALB/c and BALB/cnu/nu mice, which have distinct T‐cell dependent responses. In this study, lesion‐derived amastigotes exhibited differential protein expression in a host‐dependent manner.
Soares GHC, Barbosa GR, Stolf BS.
europepmc   +2 more sources

Analysis of energy expenditure and behavioral characteristics in different mouse strains under normal and disease conditions. [PDF]

Animal Model Exp Med
Mouse metabolic and behavioral phenotypes are tightly linked to strain, age and disease state, with distinct dysregulation in each disease model, underscoring the need for standardized preclinical experimental conditions. Abstract Background Metabolic and behavioral traits in mice exhibit substantial variability across strains, ages, and disease states,
Zeng J, Ji Y, Zou Y, Tan J, Wu T, Shen C, Huang T, Xiong S, Liu M, Yang M, Lai J, Ma J, Wan J, Fu X, Qian J, Li H, Yuan L, Cai W.   +17 more
europepmc   +2 more sources

Outbred mice as an appropriate model for evaluating the immunogenicity of vaccines against porcine circovirus 2 [PDF]

Open Veterinary Journal
Background: Porcine circovirus type 2 (PCV2) is the causative agent of porcine circovirus-associated diseases, leading to substantial economic losses in global swine production.
Vitor Barbosa Fialho Martins, Guilherme de Brito Viana, Emylli Teles de Melo Zocarato, Karen Ferraz Faria, Marina Caporusso Garcia da Silva, Taís Fukuta da Cruz, Igor Renan Honorato Gatto, Marcus Antonio Martins Buso, Ferdinando Nielsen de Almeida, Helio Jose Montassier   +9 more
doaj   +2 more sources

Lipocalin-2 Restores Mitochondrial and Antioxidant Adaptation in a Strain-Specific Manner During LPS Induced Sepsis. [PDF]

J Cell Physiol
ABSTRACT Sepsis induces profound metabolic and mitochondrial dysfunction, contributing to multiple organ injury and mortality. Lipocalin‐2 (Lcn2), an acute‐phase protein, regulates iron homeostasis and oxidative stress, but its impact on mitochondrial resilience remains poorly understood.
Kushwaha V, Kandalgaonkar MR, Singh S, Saha P, Kumar A, Yeoh BS, Vijay-Kumar M.   +6 more
europepmc   +2 more sources

Susceptibility Analysis in Several Mouse Strains Reveals Robust T-Cell Responses After Mycoplasma pneumoniae Infection in DBA/2 Mice

Frontiers in Cellular and Infection Microbiology, 2021
Mycoplasma pneumoniae (Mp) is a highly contagious respiratory pathogen responsible for human community-acquired pneumonia. The number of antibiotic-resistant Mp strains is increasing; therefore, to develop novel therapeutics, it is crucial to precisely ...
Shigeyuki Tamiya, Shigeyuki Tamiya, Shigeyuki Tamiya, Eisuke Yoshikawa, Eisuke Yoshikawa, Eisuke Yoshikawa, Koichiro Suzuki, Yasuo Yoshioka, Yasuo Yoshioka, Yasuo Yoshioka, Yasuo Yoshioka, Yasuo Yoshioka   +11 more
doaj   +1 more source

Catheter colonization and abscess formation due to Staphylococcus epidermidis with normal and small-colony-variant phenotype is mouse strain dependent. [PDF]

PLoS ONE, 2012
Coagulase-negative staphylococci (CoNS) form a thick, multilayered biofilm on foreign bodies and are a major cause of nosocomial implant-associated infections.
Gunnar Sander, Tina Börner, André Kriegeskorte, Christof von Eiff, Karsten Becker, Esther Mahabir   +5 more
doaj   +1 more source

A Combined Adjuvant TF–Al Consisting of TFPR1 and Aluminum Hydroxide Augments Strong Humoral and Cellular Immune Responses in Both C57BL/6 and BALB/c Mice

Vaccines, 2021
TFPR1 is a novel adjuvant for protein and peptide antigens, which has been demonstrated in BALB/c mice in our previous studies; however, its adjuvanticity in mice with different genetic backgrounds remains unknown, and its adjuvanticity needs to be ...
Qiao Li, Zhihua Liu, Yi Liu, Chen Liang, Jiayi Shu, Xia Jin, Chuanyou Li, Zhihua Kou   +7 more
doaj   +1 more source

Susceptibility to SARS-CoV-2 Virus Variants of Concern in Mouse Models

Проблемы особо опасных инфекций, 2022
The aim of the research was to assess the susceptibility of mice of different lines to newly emerging variants of SARS-CoV-2.Materials and methods. The SARS-CoV-2 virus strains belonging to variants of concern (VOC) circulating in the territory of the ...
A. V. Shipovalov, G. А. Kudrov, A. A. Tomilov, S. A. Bodnev, N. D. Boldyrev, A. S. Ovchinnikova, A. V. Zaikovskaya, O. S. Taranov, O. V. P’yankov, R. A. Maksyutov   +9 more
doaj   +1 more source

Repertoire of BALB/c Mice Natural Anti-Carbohydrate Antibodies: Mice vs. Humans Difference, and Otherness of Individual Animals

Frontiers in Immunology, 2017
One of the most common genetic backgrounds for mice used as a model to investigate human diseases is the inbred BALB/c strain. This work is aimed to characterize the pattern of natural anti-carbohydrate antibodies present in the serum of 20 BALB/c mice ...
Daniel Bello-Gil, Nailya Khasbiullina, Nadezhda Shilova, Nicolai Bovin, Rafael Mañez, Rafael Mañez   +5 more
doaj   +1 more source

Preliminary Study the Effect of Galbanic Acid on the Efficacy of Radiation Therapy on O26 Tumor Cells Implanted In Balb-C Mice [PDF]

Iranian Journal of Medical Physics
Introduction: In the present study we used Galbanic acid (GA) combined with radiation therapy to raise radiation efficacy. GA extracted from Ferula species and have anti-cancer properties.
Morteza Rezaei kahkha, Shokouhozaman Soleymanifard, mehrdad iranshahi, samaneh soudmand salarabadi, elham tavakkoli, amir fotovati, Najme rezaei dovom   +6 more
doaj   +1 more source