Results 11 to 20 of about 80,606 (215)

Effect of cyclo-L-prolylglycine on pain response thresholds and morphine-induced analgesia in inbred BALB/c and C57Bl/6 mice

Фармакокинетика и Фармакодинамика
Relevance. Cyclo-L-prolylglycine (CPG), discovered as an endogenous compound in the central nervous system, is involved in the formation of a reaction to emotional stress in rodents with a pronounced fear reaction and has an analgesic effect in vivo ...
A. V. Nadorova, K. N. Koliasnikova, I. V. Chernyakova, L. G. Kolik   +3 more
doaj   +4 more sources

Repertoire of BALB/c Mice Natural Anti-Carbohydrate Antibodies: Mice vs. Humans Difference, and Otherness of Individual Animals [PDF]

Frontiers in Immunology, 2017
One of the most common genetic backgrounds for mice used as a model to investigate human diseases is the inbred BALB/c strain. This work is aimed to characterize the pattern of natural anti-carbohydrate antibodies present in the serum of 20 BALB/c mice ...
Daniel Bello-Gil, Nailya Khasbiullina, Nadezhda Shilova, Nicolai Bovin, Rafael Mañez, Rafael Mañez   +5 more
doaj   +3 more sources

Characterization of Mouse-Adapted Marburg and Ravn Viruses in Inbred BALB/c and Outbred CD-1 Mice. [PDF]

J Infect Dis
Abstract Marburgviruses cause severe hemorrhagic disease in humans, yet characterization of rodent models for pathogenesis and medical countermeasure development remains limited. Here, we investigated clinical course, blood chemistry, viral dissemination, and mucosal viral detection in inbred BALB/c and outbred CD-1 mice infected with
Davies KA, Welch SR, Coleman-McCray JD, Sorvillo TE, Aida-Ficken V, Jain S, Albariño CG, He B, Spiropoulou CF, Spengler JR.   +9 more
europepmc   +3 more sources

Experimental infection of inbred BALB/c and A/J mice with Massachusetts and Brazilian strains of infectious bronchitis virus (IBV) [PDF]

Archives of Virology, 2015
The ability of avian coronaviruses to replicate in mice was investigated to investigate interspecies transmission. Two inbred mouse strains (BALB/c and A/J) with different genetic backgrounds were inoculated with the avian coronavirus strains Mass and BR-I and monitored for at least 10 days.
Martini, Matheus Cavalheiro, Gameiro, Jacy, Cardoso, Tereza Cristina, Caserta, Leonardo Cardia, Gualberto, Ana Carolina, Keid, Lara Borges, Oliveira, Tricia Maria Ferreira de Sousa, Santos, Márcia Mercês Aparecida Bianchi dos, Arns, Clarice Weis, Ferreira, Helena Lage   +9 more
openaire   +4 more sources

The Inflammatory Response in the Murine Ovalbumin-Induced Skin Inflammation Model Is Robust Despite Major Gut Microbiota Differences. [PDF]

Clin Transl Sci
ABSTRACT Valid pre‐clinical animal models are essential for effective drug development in inflammatory skin diseases like atopic dermatitis. Most murine models exhibit low‐to‐moderate inflammatory responses with significant variability, undermining their validity and contributing to high drug attrition rates.
Henriksen IW, Bartholdy C, Koch J, Stefanova DV, Hansen CHF, Hansen AK.   +5 more
europepmc   +2 more sources

Establishment of a BALB/c Mouse Model for Photoaged Skin: Insights into UV-Induced Dermatological Changes. [PDF]

Skin Res Technol
ABSTRACT Background Photoaging, primarily induced by prolonged ultraviolet (UV) radiation exposure, significantly alters skin structure and function, necessitating models for deeper understanding and intervention development. This study aims to establish a BALB/c mouse model for investigating photoaging, leveraging their haired skin and genetic ...
Huynh CB, Vu NB, The Van T, Van Pham P.
europepmc   +2 more sources

Study of protective properties of butyrylcholinesterase in acute anticholinesterase poisoning on BChE-KO and BALB/c mice [PDF]

Research Results in Pharmacology, 2020
Introduction: The article presents the results of studying the protective properties of recombinant human butyrylcholinesterase (rhBChE) in a model of acute anticholinesterase poisoning in mice knocked out for the BChE gene.
Viktor A. Palikov, Yuliya A. Palikova, Igor A. Dyachenko   +2 more
doaj   +5 more sources

A BALB/c IGHV Reference Set, Defined by Haplotype Analysis of Long-Read VDJ-C Sequences From F1 (BALB/c x C57BL/6) Mice

Frontiers in Immunology, 2022
The immunoglobulin genes of inbred mouse strains that are commonly used in models of antibody-mediated human diseases are poorly characterized. This compromises data analysis.
Katherine J. L. Jackson, Justin T. Kos, William Lees, William S. Gibson, Melissa Laird Smith, Ayelet Peres, Gur Yaari, Martin Corcoran, Christian E. Busse, Mats Ohlin, Corey T. Watson, Andrew M. Collins   +11 more
doaj   +2 more sources

An Inbred Epilepsy-Prone Substrain of BALB/c Mice Shows Absence of the Corpus Callosum, an Abnormal Projection to the Basal Forebrain, and Bilateral Projections to the Thalamus [PDF]

Cerebral Cortex, 1994
BALB/c mice lack a corpus callosum in about 11% of the population. Two inbred substrains of BALB/c mice, epilepsy-prone (EP) and epilepsy-resistant (ER), have been examined to determine whether these substrains differ in regard to corpus callosum morphology.
Morin, Catherine L, Dolina, Svetlana, Robertson, Richard T, Ribak, Charles E   +3 more
openaire   +5 more sources

Dipeptide cholecystokinin-4 analog attenuates anxiety in "high-emotional" mice BALB/c and in ethanol-withdrawn rats: comparison with phenazepam

Фармакокинетика и Фармакодинамика, 2017
Anxiolytic effects of dipeptide endogenous cholecystokinin tetrapeptide analogue GB-115 at the dose range 0,25-2,0 mg/ kg after oral administration were studied in rodents with high emotionality.
L. G. Kolik, A. V. Nadorova, T. A. Gudasheva, V. A. Martyanov, S. B. Seredenin   +4 more
doaj   +2 more sources