Results 31 to 40 of about 80,040 (177)

Advancing Type 1 Diabetes Treatment: 3 PM‐Oriented Innovations in Islet Transplantation and Biomaterial Engineering

open access: yesDiabetes/Metabolism Research and Reviews, Volume 42, Issue 6, September 2026.
ABSTRACT Type 1 Diabetes (T1D) is an autoimmune disorder marked by the immune‐mediated destruction of pancreatic β‐cells, resulting in insulin deficiency and dysregulated glucose control. Current therapies—such as insulin replacement and artificial pancreas systems—manage symptoms but fail to restore endogenous β‐cell function or halt disease ...
Fatemeh Sabet Sarvestani   +4 more
wiley   +1 more source

The contribution of natural killer complex loci to the development of experimental cerebral malaria.

open access: yesPLoS ONE, 2014
BackgroundThe Natural Killer Complex (NKC) is a genetic region of highly linked genes encoding several receptors involved in the control of NK cell function.
Diana S Hansen   +7 more
doaj   +1 more source

Dissecting the Strain and Sex Specific Connectome Signatures of Unanesthetized C57BL/6J and DBA/2J Mice Using Magnetic Resonance Imaging

open access: yesGenes, Brain and Behavior, Volume 25, Issue 4, August 2026.
C57BL/6J and DBA/2J mice were used to investigate strain and sex‐specific features of the brain connectome in awake animals using magnetic resonance imaging (MRI). By combining resting‐state and diffusion MRI, we found significant differences in the motor, sensory, limbic, and salience networks between C57BL/6J and DBA/2J mice.
Tanzil M. Arefin   +4 more
wiley   +1 more source

Genetic and morphometric characteristics of Korean wild mice (KWM/Hym) captured at Chuncheon, South Korea

open access: yesLaboratory Animal Research, 2018
Laboratory inbred mice are used widely and commonly in biomedical research, but inbred mice do not have a big enough gene pool for the research. In this study, genetic and morphometric analyses were performed to obtain data on the characteristics of a ...
Hajin Nam   +5 more
doaj   +1 more source

Elucidating the characteristics of Mx1 and resistance to influenza A virus subtype H1N1 in the newly developed KWM/Hym mice

open access: yesLaboratory Animal Research, 2022
Background Inbred mice have several advantages, including genetic similarity to humans, a well-established gene manipulation system, and strong tolerance to inbreeding.
Hajin Nam   +8 more
doaj   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

open access: yesPhytotherapy Research, Volume 40, Issue 7, Page 4676-4709, July 2026.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández   +5 more
wiley   +1 more source

Genetic dissection of the Canq1 locus governing variation in extent of the collateral circulation. [PDF]

open access: yesPLoS ONE, 2012
Native (pre-existing) collaterals are arteriole-to-arteriole anastomoses that interconnect adjacent arterial trees and serve as endogenous bypass vessels that limit tissue injury in ischemic stroke, myocardial infarction, coronary and peripheral artery ...
Shiliang Wang   +4 more
doaj   +1 more source

Advances in Polyethyleneimine‐Derived Nanoformulations

open access: yesSmall Science, Volume 6, Issue 7, July 2026.
This article illustrates the cytotoxic effects of polyethyleneimine (PEI) on cell membranes and mitochondria, the strategies employed to mitigate PEI‐associated toxicity through chemical modification, PEGylation, and structural optimization, and the major types of PEI‐based formulations developed for the delivery of therapeutic drugs, nucleic acids ...
Mohamed S. Attia   +2 more
wiley   +1 more source

Lysed Enterococcus faecalis FK-23 (LFK) Suppressing Allergic Responses in Mouse Models

open access: yesAllergology International, 2005
Recently, several clinical trials have been published to discuss the possibility of probiotic supplementation, especially some products of lactic acid bacteria such as Lactobacillus and Bifidobacterium strains, in prevention and treatment of allergic ...
Takashi Shimada   +6 more
doaj   +1 more source

Sex Differences in Behavioral Responses to Chronic Unpredictable Mild Stress in Swiss Mice

open access: yesEuropean Journal of Neuroscience, Volume 64, Issue 2, July 2026.
Behavioral changes induced by chronic unpredictable mild stress develop over time in a sex‐dependent manner in Swiss mice. Male and female mice exhibit distinct adaptive strategies to stress in the open‐field exploration profile. Changes in forced‐swimming immobility were robust only after 8 weeks of stress in both sexes. However, only females showed a
Rachel de Barros‐Telles   +6 more
wiley   +1 more source

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