Results 41 to 50 of about 80,040 (177)

The Converging Effects of Different Categories of Antidepressants on the Brain: A Systematic Meta‐Analysis of Public Transcriptional Profiling Data From the Hippocampus and Cortex

Journal of Neurochemistry, Volume 170, Issue 7, July 2026.
Understanding the congruent effects of different types of antidepressant treatments on sensitive brain regions, such as the hippocampus and cortex, can highlight essential mechanisms of action. We used a systematic meta‐analysis of public transcriptional profiling datasets to identify genes and functional gene sets that are differentially expressed ...
Eva M. Geoghegan, Megan H. Hagenauer, Erin Hernandez, Sophia Espinoza, Elizabeth I. Flandreau, Phi T. Nguyen, Adrienne N. Santiago, Mubashshir Ra’eed Bhuiyan, Sophie Mensch, Stanley J. Watson Jr., Huda Akil, René Hen   +11 more
wiley   +1 more source

The Preventive and Curative Effects of Fresh Garlic Extract And its Aerial Parts on Fibrosarcoma in Balb/c Mice

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2012
Introduction: Garlic has been demonstrated to have anticancer activity in some studies; however its effect on fibrosarcoma is not evident. This study intends to examine the preventive and curative effects of fresh garlic extract and its aerial parts on ...
M Rafieian-kopaei, M Hosseini, A Pilehvarian, F Taji, H Shirzad   +4 more
doaj  

Investigation of natural infection of BALB C mice by Bartonella henselae

Brazilian Journal of Infectious Diseases
Specific Pathogen-Free (SPF) animals are bred and maintained to exclude pathogens associated with significant morbidity or mortality, which may pose a risk to research replicability.
Luciene Silva dos Santos, Sayros Akyro Soares Martins, Francine Ramos Scheffer, Alexandre Seiji Maekawa, Rafaela de Paula Silva, Gabriel Rabelo de Araújo, Paulo Eduardo Neves Ferreira Velho, Marina Rovani Drummond   +7 more
doaj   +1 more source

Infection of inbred BALB/c and C57BL/6 and outbred Institute of Cancer Research mice with the emerging H7N9 avian influenza virus

Emerging Microbes & Infections, 2013
A new avian-origin influenza virus A (H7N9) recently crossed the species barrier and infected humans; therefore, there is an urgent need to establish mammalian animal models for studying the pathogenic mechanism of this strain and the immunological response.
Zhu, Zhaoqin, Yang, Yuqin, Feng, Yanling, Shi, Bisheng, Chen, Lixiang, Zheng, Ye, Tian, Di, Song, Zhigang, Xu, Chunhua, Qin, Boyin, Zhang, Xiaonan, Guan, Wencai, Liu, Fang, Yang, Tao, Yang, Hua, Zeng, Dong, Zhou, Wenjiang, Hu, Yunwen, Zhou, Xiaohui   +18 more
openaire   +2 more sources

The effects of levetiracetam and a new 4-phenylpyrrolidone derivative GIZh-290 in a closed cross-maze in BALB/c and C57BL / 6 mice

Фармакокинетика и Фармакодинамика, 2017
The study was aimed to compare the psychopharmacological effects of 2 anticonvulsant drugs levetiracetam ((S)-2-(2-oxopyrrolidin-1-yl) butanamide) and the new compound, GIZh-290 (2-oxo-4-phenylpyrrolidine-1-yl) acetic acid) on behavioral spectra of ...
I. G. Kovalev, E. V. Vasileva, R. O. Bokov, R. M. Salimov, G. I. Kovalev   +4 more
doaj  

Effect of dietary cholesterol and taurocholate on cholesterol 7 alpha-hydroxylase and hepatic LDL receptors in inbred mice

Journal of Lipid Research, 1993
Compared to BALB/c mice, inbred C57BL/6 mice are more susceptible to developing fatty streak atherosclerotic lesions when fed a cholesterol-rich diet containing taurocholate. We examined the metabolic basis for the taurocholate requirement.
S Dueland, J Drisko, L Graf, D Machleder, AJ Lusis, RA Davis   +5 more
doaj   +1 more source

An Inbred Epilepsy-Prone Substrain of BALB/c Mice Shows Absence of the Corpus Callosum, an Abnormal Projection to the Basal Forebrain, and Bilateral Projections to the Thalamus [PDF]

Cerebral Cortex, 1994
BALB/c mice lack a corpus callosum in about 11% of the population. Two inbred substrains of BALB/c mice, epilepsy-prone (EP) and epilepsy-resistant (ER), have been examined to determine whether these substrains differ in regard to corpus callosum morphology.
Morin, Catherine L, Dolina, Svetlana, Robertson, Richard T, Ribak, Charles E   +3 more
openaire   +4 more sources

Lipocalin‐2 Restores Mitochondrial and Antioxidant Adaptation in a Strain‐Specific Manner During LPS Induced Sepsis

Journal of Cellular Physiology, Volume 241, Issue 6, June 2026.
ABSTRACT Sepsis induces profound metabolic and mitochondrial dysfunction, contributing to multiple organ injury and mortality. Lipocalin‐2 (Lcn2), an acute‐phase protein, regulates iron homeostasis and oxidative stress, but its impact on mitochondrial resilience remains poorly understood.
Vinita Kushwaha, Mrunmayee R. Kandalgaonkar, Sukhvinder Singh, Piu Saha, Ashok Kumar, Beng San Yeoh, Matam Vijay‐Kumar   +6 more
wiley   +1 more source

Comparison of the behaviour of three strains of laboratory mice in the climbing test

Animal Welfare, Etológia és Tartástechnológia
In our study, we tested three commonly used strains of laboratory mice in a simple behavioural test. In the climbing test, we looked at the time of the first climb and the number of climbs of the different strains during the 5-minute test time, depending
Henrietta Kinga Török, Boróka Bárdos, Orsolya Ivett Hoffmann   +2 more
doaj   +1 more source

Endogenous MMTV proviruses induce susceptibility to both viral and bacterial pathogens.

PLoS Pathogens, 2006
Most inbred mice carry germline proviruses of the retrovirus, mouse mammary tumor virus (MMTV) (called Mtvs), which have multiple replication defects. A BALB/c congenic mouse strain lacking all endogenous Mtvs (Mtv-null) was resistant to MMTV oral and ...
Sanchita Bhadra, Mary M Lozano, Shelley M Payne, Jaquelin P Dudley   +3 more
doaj   +1 more source