Results 61 to 70 of about 80,606 (215)

Lipocalin‐2 Restores Mitochondrial and Antioxidant Adaptation in a Strain‐Specific Manner During LPS Induced Sepsis

Journal of Cellular Physiology, Volume 241, Issue 6, June 2026.
ABSTRACT Sepsis induces profound metabolic and mitochondrial dysfunction, contributing to multiple organ injury and mortality. Lipocalin‐2 (Lcn2), an acute‐phase protein, regulates iron homeostasis and oxidative stress, but its impact on mitochondrial resilience remains poorly understood.
Vinita Kushwaha, Mrunmayee R. Kandalgaonkar, Sukhvinder Singh, Piu Saha, Ashok Kumar, Beng San Yeoh, Matam Vijay‐Kumar   +6 more
wiley   +1 more source

Mechanisms controlling anaemia in Trypanosoma congolense infected mice. [PDF]

, 2009
Trypanosoma congolense are extracellular protozoan parasites of the blood stream of artiodactyls and are one of the main constraints on cattle production in Africa.
de Angelis Martin Hrabé, Eckard Wolf, Naessens, Jan, Fuchs Helmut, Hulme, Helen, Kemp, Stephen, Alimohammadian, M.H., Wolf, Eckard, Morris Agaba, Noyes, Harry A., Hrabě de Angelis, M., de Angelis, Martin Hrabé, Agaba, M., Angelis, M.H. de, Mohammad H Alimohammadian, Martin Hrabé de Angelis, Brass Andy, Hulme Helen, Delnaz Rosh, Rathkolb, Birgit, Roshandel, Delnaz, Noyes Harry A., Rathkolb, B., Iraqi, Fuad, Fuchs, H., Hrabé de Angelis, Martin, Stephen Kemp, Jan Naessens, Wolf, E., Naessens Jan, Alimohammadian Mohammad H., Gailus-Durner, V., Gailus-Durner Valerie, Martin Hrabe ́ De Angelis, Kemp, S., Brass, Andy, Helmut Fuchs, Agaba Morris, Iraqi Fuad, Harry A. Noyes, Andy Brass, Noyes, H.A., Helen Hulme, Agaba, Morris, Kemp, Stephen J., Iraqi, F., Iraqi, F.A., Kemp Stephen, Brass, A., Harry A Noyes, Roshandel, D., Wolf Eckard, Rathkolb Birgit, Naessens, J., Delnaz Roshandel, Birgit Rathkolb, Brass, Andy; id_orcid, Alimohammadian, Mohammad H., Fuchs, Helmut, Fuad Iraqi, Wolf, Eckhard, Valerie Gailus-Durner, Hulme, H., Gailus-Durner, Valerie, Mohammad H. Alimohammadian, Roshandel Delnaz   +65 more
core   +1 more source

Gamma‐irradiated Newcastle disease virus: an alternative inactivated oncolytic virotherapy

Immunology &Cell Biology, Volume 104, Issue 5, Page 473-484, May‐June 2026.
To overcome biological risks associated with using live NDV as an oncolytic therapy, we developed gamma‐NDV as a safer alternative. Using a murine model for skin cancer, we show that intratumor administration of gamma‐NDV outperformed live‐NDV in terms of reducing tumor growth and improving overall animal survival. Abstract Newcastle disease virus (NDV)
Eve V Kennedy, Yimin Chuah, Amal H Mostafa, Chloe J Gates, Jade Foeng, Todd S Norton, Shaun R McColl, Iain Comerford, Justin B Davies, Farhid Hemmatzadeh, Mohammed Alsharifi   +10 more
wiley   +1 more source

Investigation of natural infection of BALB C mice by Bartonella henselae

Brazilian Journal of Infectious Diseases
Specific Pathogen-Free (SPF) animals are bred and maintained to exclude pathogens associated with significant morbidity or mortality, which may pose a risk to research replicability.
Luciene Silva dos Santos, Sayros Akyro Soares Martins, Francine Ramos Scheffer, Alexandre Seiji Maekawa, Rafaela de Paula Silva, Gabriel Rabelo de Araújo, Paulo Eduardo Neves Ferreira Velho, Marina Rovani Drummond   +7 more
doaj   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, Volume 13, Issue 22, 17 April 2026.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

The Preventive and Curative Effects of Fresh Garlic Extract And its Aerial Parts on Fibrosarcoma in Balb/c Mice

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2012
Introduction: Garlic has been demonstrated to have anticancer activity in some studies; however its effect on fibrosarcoma is not evident. This study intends to examine the preventive and curative effects of fresh garlic extract and its aerial parts on ...
M Rafieian-kopaei, M Hosseini, A Pilehvarian, F Taji, H Shirzad   +4 more
doaj  

Infection of inbred BALB/c and C57BL/6 and outbred Institute of Cancer Research mice with the emerging H7N9 avian influenza virus

Emerging Microbes & Infections, 2013
A new avian-origin influenza virus A (H7N9) recently crossed the species barrier and infected humans; therefore, there is an urgent need to establish mammalian animal models for studying the pathogenic mechanism of this strain and the immunological response.
Zhu, Zhaoqin, Yang, Yuqin, Feng, Yanling, Shi, Bisheng, Chen, Lixiang, Zheng, Ye, Tian, Di, Song, Zhigang, Xu, Chunhua, Qin, Boyin, Zhang, Xiaonan, Guan, Wencai, Liu, Fang, Yang, Tao, Yang, Hua, Zeng, Dong, Zhou, Wenjiang, Hu, Yunwen, Zhou, Xiaohui   +18 more
openaire   +2 more sources

Functional Segregation of Pancreatic Microcirculation Reveals Sex‐Dependent Microhemodynamic Signatures

Comprehensive Physiology, Volume 16, Issue 2, April 2026.
Pancreatic exocrine microcirculation exhibits sexual dimorphism arising from steroid–genetic interactions. Laser Doppler flowmetry combined with wavelet analysis identifies a male passive coupling phenotype aligned with systemic pressure and a female active vasomotion phenotype driven by ERβ‐mediated, NO‐dependent oscillations.
Yuan Li, Yingyu Wang, Bing Wang, Qin Ouyang, Weiqi Liu, Xiang Xu, Xu Zhang, Mingming Liu, Ruijuan Xiu   +8 more
wiley   +1 more source

Master of Science [PDF]

, 2017
thesisBALB/c mice have been used to study multiple diseases that cause inflammation such as Lyme arthritis, rheumatoid arthritis, and systemic lupus erythematosus.
Fisher, Colleen Melissa
core  

A Behavioral Comparison of Four Inbred Strains of Mice

, 2010
Isogenic, or inbred, mouse strains are currently the experimental subjects of choice in laboratory studies focused on genetics, pharmacology, and psychological issues.
Wood, Erin
core   +1 more source