Compared to BALB/c mice, inbred C57BL/6 mice are more susceptible to developing fatty streak atherosclerotic lesions when fed a cholesterol-rich diet containing taurocholate. We examined the metabolic basis for the taurocholate requirement.
S Dueland +5 more
doaj +1 more source
Abstract graph of the in vivo immunomodulatory activity of polysaccharide based on a cyclophosphamide‐induced mouse model. ABSTRACT The immune system serves as the primary defense mechanism against pathogens and plays a vital role in maintaining host homeostasis. In recent years, natural polysaccharides have emerged as promising immunomodulators due to
Wenlei Nie +3 more
wiley +1 more source
Comparison of the behaviour of three strains of laboratory mice in the climbing test
In our study, we tested three commonly used strains of laboratory mice in a simple behavioural test. In the climbing test, we looked at the time of the first climb and the number of climbs of the different strains during the 5-minute test time, depending
Henrietta Kinga Török +2 more
doaj +1 more source
Endogenous MMTV proviruses induce susceptibility to both viral and bacterial pathogens.
Most inbred mice carry germline proviruses of the retrovirus, mouse mammary tumor virus (MMTV) (called Mtvs), which have multiple replication defects. A BALB/c congenic mouse strain lacking all endogenous Mtvs (Mtv-null) was resistant to MMTV oral and ...
Sanchita Bhadra +3 more
doaj +1 more source
Created in BioRender. Haralambie, O. (2025) https://BioRender.com/dh5ly89. ABSTRACT Digestive disorders such as inflammatory bowel disease (IBD) and colorectal cancer are among the most significant global health challenges, largely driven by chronic inflammation and oxidative stress.
Oana‐Roxana Haralambie, Sanda Andrei
wiley +1 more source
Avaliação temporal dos efeitos de estresse de contenção no frio sobre os comportamentos relacionados a ansiedade e depressão em duas linhagens de camundongos fêmeas: Swiss e C57BL/6J [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2013A resposta de estresse tem valor adaptativo na sobrevivência das espécies, porém quando há uma ...
Marchette, Renata Cristina Nunes
core
Comparison of Metabolomic Profiles of Organs in Mice of Different Strains Based on SPME-LC-HRMS
Given that the extent to which genetics alters the metabolomic profile of tissues is still poorly understood, the current study aimed to characterize and investigate the metabolite profiles of brain, liver, kidney and skeletal muscle of two common mouse ...
Katarzyna Burlikowska +5 more
doaj +1 more source
CFTR regulates early pathogenesis of chronic obstructive lung disease in βENaC-overexpressing mice. [PDF]
BACKGROUND: Factors determining the onset and severity of chronic obstructive pulmonary disease remain poorly understood. Previous studies demonstrated that airway surface dehydration in βENaC-overexpressing (βENaC-Tg) mice on a mixed genetic background ...
Bjarki Johannesson +4 more
doaj +1 more source
The Japanese Macaque as a Diabetes Recipient Animal Model for Porcine Islet Xenotransplantation
Porcine islet xenotransplantation is effective for severe diabetes; however, preclinical studies are essential. In this study, we evaluated the suitability of the Japanese macaque as a recipient model for islet xenotransplantation, including identifying the preferred method to induce diabetes.
Naoaki Sakata +4 more
wiley +1 more source
Most of the response elicited against Wolbachia surface protein in filarial nematode infection is due to the infective larval stage [PDF]
Immune responses to the intracellular Wolbachia bacteria of filarial nematodes are thought to contribute to the pathologic process of filarial infection.
Lamb, Tracey J +7 more
core +1 more source

