Results 71 to 80 of about 89,973 (224)

Differential Effects on Survival, Humoral Immune Responses and Brain Lesions in Inbred BALB/C, CBA/CA, and C57BL/6 Mice Experimentally Infected withNeospora caninumTachyzoites [PDF]

ISRN Parasitology, 2013
C57BL/6, BALB/c, and CBA/Ca mouse strains with different MHC-I haplotypes were compared with respect to susceptibility toNeospora caninuminfection. Groups of 5 mice received , , or tachyzoites of the NC-Liverpool isolate by intraperitoneal injection and were observed for disease symptoms.
Tanja Mols-Vorstermans, Andrew Hemphill, Thierry Monney, Dick Schaap, Eveline Boerhout   +4 more
openaire   +4 more sources

Sex‐dependent effects of environmental enrichment on mood‐related behaviors, central and peripheral BDNF, and adrenal catecholamine enzymes in mice

Physiological Reports, Volume 14, Issue 7, April 2026.
Abstract Housing conditions, particularly environmental enrichment (EE), can influence experimental outcomes and welfare. While EE is generally regarded as beneficial, a male bias exists in research supporting this. This study investigated whether sex differences exist in levels of BDNF in the brain and peripheral tissues in environmentally enriched ...
M. F. Herselman, S. Y. Luo, L. Y. Lin, X. F. Zhou, L. Bobrovskaya   +4 more
wiley   +1 more source

The effects of levetiracetam and a new 4-phenylpyrrolidone derivative GIZh-290 in a closed cross-maze in BALB/c and C57BL / 6 mice

Фармакокинетика и Фармакодинамика, 2017
The study was aimed to compare the psychopharmacological effects of 2 anticonvulsant drugs levetiracetam ((S)-2-(2-oxopyrrolidin-1-yl) butanamide) and the new compound, GIZh-290 (2-oxo-4-phenylpyrrolidine-1-yl) acetic acid) on behavioral spectra of ...
I. G. Kovalev, E. V. Vasileva, R. O. Bokov, R. M. Salimov, G. I. Kovalev   +4 more
doaj  

Endogenous MMTV proviruses induce susceptibility to both viral and bacterial pathogens.

PLoS Pathogens, 2006
Most inbred mice carry germline proviruses of the retrovirus, mouse mammary tumor virus (MMTV) (called Mtvs), which have multiple replication defects. A BALB/c congenic mouse strain lacking all endogenous Mtvs (Mtv-null) was resistant to MMTV oral and ...
Sanchita Bhadra, Mary M Lozano, Shelley M Payne, Jaquelin P Dudley   +3 more
doaj   +1 more source

In utero ultrafine particulate matter exposure causes offspring pulmonary immunosuppression. [PDF]

, 2019
Early life exposure to fine particulate matter (PM) in air is associated with infant respiratory disease and childhood asthma, but limited epidemiological data exist concerning the impacts of ultrafine particles (UFPs) on the etiology of childhood ...
Chang, Richard C-A, Golding, Michael C, Johnson, Natalie M, Langley, Rebecca, Lau, Carmen, Leal, Jeann, Li, Yixin, Molina, Mario J, Myatt, Louise G, Pulczinski, Jairus, Raju, Muppala, Rodrigues-Hoffmann, Aline, Rychlik, Kristal A, Secrest, Jeremiah R, Zamora, Misti L, Zhang, Renyi   +15 more
core  

A Murine Database of Structural Variants Identifies A Candidate Gene for a Spontaneous Murine Lymphoma Model

Advanced Science, Volume 13, Issue 17, 23 March 2026.
We analyzed long‐read genomic sequencing data obtained from 40 inbred mouse strains to produce a large database of structural variants. This dataset captures the major types of structural variants, which includes deletions, insertions, duplications, and inversions.
Wenlong Ren, Zhuoqing Fang, Egor Dolzhenko, Christopher T. Saunders, Zhuanfen Cheng, Victoria Popic, Gary Peltz   +6 more
wiley   +1 more source

Comparison of the behaviour of three strains of laboratory mice in the climbing test

Animal Welfare, Etológia és Tartástechnológia
In our study, we tested three commonly used strains of laboratory mice in a simple behavioural test. In the climbing test, we looked at the time of the first climb and the number of climbs of the different strains during the 5-minute test time, depending
Henrietta Kinga Török, Boróka Bárdos, Orsolya Ivett Hoffmann   +2 more
doaj   +1 more source

Comparison of Metabolomic Profiles of Organs in Mice of Different Strains Based on SPME-LC-HRMS

Metabolites, 2020
Given that the extent to which genetics alters the metabolomic profile of tissues is still poorly understood, the current study aimed to characterize and investigate the metabolite profiles of brain, liver, kidney and skeletal muscle of two common mouse ...
Katarzyna Burlikowska, Iga Stryjak, Joanna Bogusiewicz, Bogumiła Kupcewicz, Karol Jaroch, Barbara Bojko   +5 more
doaj   +1 more source

CFTR regulates early pathogenesis of chronic obstructive lung disease in βENaC-overexpressing mice. [PDF]

PLoS ONE, 2012
BACKGROUND: Factors determining the onset and severity of chronic obstructive pulmonary disease remain poorly understood. Previous studies demonstrated that airway surface dehydration in βENaC-overexpressing (βENaC-Tg) mice on a mixed genetic background ...
Bjarki Johannesson, Stephanie Hirtz, Jolanthe Schatterny, Carsten Schultz, Marcus A Mall   +4 more
doaj   +1 more source

Agouti C57BL/6N embryonic stem cells for mouse genetic resources. [PDF]

, 2009
We report the characterization of a highly germline competent C57BL/6N mouse embryonic stem cell line, JM8. To simplify breeding schemes, the dominant agouti coat color gene was restored in JM8 cells by targeted repair of the C57BL/6 nonagouti mutation ...
Beier, David R, Bradley, Allan, Liang, Qi, Lloyd, Kent C, Moran, Jennifer L, Pettitt, Stephen J, Prosser, Haydn M, Rairdan, Xin Y, Skarnes, William C   +8 more
core   +1 more source