Results 91 to 100 of about 80,606 (215)
Nitric oxide (NO) is one of dozens of lipophilic small molecules that is synthesized from amino acid L-Arginine, O2 and NADPH by nitric oxide synthase (NOS). There is increasing evidence that NO is an important molecular messenger involved in a wide variety of biological processes in different systems. One of the isoforms of NOS enzyme called inducible
Moslem Najafi +4 more
openaire +1 more source
Abstract Housing conditions, particularly environmental enrichment (EE), can influence experimental outcomes and welfare. While EE is generally regarded as beneficial, a male bias exists in research supporting this. This study investigated whether sex differences exist in levels of BDNF in the brain and peripheral tissues in environmentally enriched ...
M. F. Herselman +4 more
wiley +1 more source
The CTLA-4 and PD-1/PD-L1 inhibitory pathways independently regulate host resistance to Plasmodium-induced acute immune pathology. [PDF]
The balance between pro-inflammatory and regulatory immune responses in determining optimal T cell activation is vital for the successful resolution of microbial infections.
Couper, Kevin N +44 more
core +1 more source
Nitric oxide (NO) has been involved in many pathophysiological brain processes. Recently, we showed that neuronal nitric oxide synthase (nNOS)-mediated decrease in NO production is involved in memory impairment induced by chronic mild stress (CMS) in BALB/c mice.
María Laura, Palumbo +3 more
openaire +2 more sources
Adipose tissue-derived mesenchymal stem cells (AD-MSCs) have been shown to be capable of differentiating into multiple cell type and exert immunomodulatory effects.
Pourfathollah, Ali Akbar +5 more
core +1 more source
The role of GABAB(1) receptor isoforms in anxiety and depression : genetic and pharmacological studies in the mouse [PDF]
Anxiety and depression disorders represent common, serious and growing health problems world-wide. The neurobiological basis of anxiety and depression, however, remains poorly understood.
Jacobson, Laura Helen
core +1 more source
Myeloma Proteins from NZB and BALB/c Mice: Structural and Functional Differences [PDF]
Structural and functional analyses of myeloma immunoglobulins from inbred BALB/c mice and humans have provided important insights into the structure of the antibody molecule and the expression and evolution of antibody genes.
Weigert, M. +5 more
core
Evaluation of an outbred mouse model for Francisella tularensis vaccine development and testing.
Francisella tularensis (Ft) is a biothreat agent for which there is no FDA-approved human vaccine. Currently, there are substantial efforts underway to develop both vaccines and the tools to assess these vaccines.
Raju Sunagar +5 more
doaj +1 more source
To elucidate requirements for in vitro sperm capacitation in inbred BALB/c mice, osmolarity, calcium and lactate were optimized using modified simplex optimization medium (mKSOM).
449473 +11 more
core +1 more source
Heligmosomoides polygyrus: Resistance in inbred, outbred, and selected mice
Mice reared selectively as high- and low- immune responders to reinfection with Heligmosomoides polygyrus showed extremes of resistance and susceptibility after infection when compared to inbred BALB/C, DBA/I, CBA, and SJL/J and outbred Quackenbush (Q ...
Zhong S., Dobson C.
core +1 more source

