Results 51 to 60 of about 89,973 (224)
Characterization of the T cell receptor repertoire causing collagen arthritis in mice [PDF]
Collagen type II-induced arthritis (CIA) is generated in susceptible rodent strains by intradermal injections of homologous or heterologous native type II collagen in complete Freund's adjuvant.
Hood, Leroy E. +3 more
core +2 more sources
Laboratory inbred mice are used widely and commonly in biomedical research, but inbred mice do not have a big enough gene pool for the research. In this study, genetic and morphometric analyses were performed to obtain data on the characteristics of a ...
Hajin Nam +5 more
doaj +1 more source
Background Inbred mice have several advantages, including genetic similarity to humans, a well-established gene manipulation system, and strong tolerance to inbreeding.
Hajin Nam +8 more
doaj +1 more source
Abstract graph of the in vivo immunomodulatory activity of polysaccharide based on a cyclophosphamide‐induced mouse model. ABSTRACT The immune system serves as the primary defense mechanism against pathogens and plays a vital role in maintaining host homeostasis. In recent years, natural polysaccharides have emerged as promising immunomodulators due to
Wenlei Nie +3 more
wiley +1 more source
Genetic dissection of the Canq1 locus governing variation in extent of the collateral circulation. [PDF]
Native (pre-existing) collaterals are arteriole-to-arteriole anastomoses that interconnect adjacent arterial trees and serve as endogenous bypass vessels that limit tissue injury in ischemic stroke, myocardial infarction, coronary and peripheral artery ...
Shiliang Wang +4 more
doaj +1 more source
Nitric oxide (NO) is one of dozens of lipophilic small molecules that is synthesized from amino acid L-Arginine, O2 and NADPH by nitric oxide synthase (NOS). There is increasing evidence that NO is an important molecular messenger involved in a wide variety of biological processes in different systems. One of the isoforms of NOS enzyme called inducible
Moslem Najafi +4 more
openaire +1 more source
Created in BioRender. Haralambie, O. (2025) https://BioRender.com/dh5ly89. ABSTRACT Digestive disorders such as inflammatory bowel disease (IBD) and colorectal cancer are among the most significant global health challenges, largely driven by chronic inflammation and oxidative stress.
Oana‐Roxana Haralambie, Sanda Andrei
wiley +1 more source
Lysed Enterococcus faecalis FK-23 (LFK) Suppressing Allergic Responses in Mouse Models
Recently, several clinical trials have been published to discuss the possibility of probiotic supplementation, especially some products of lactic acid bacteria such as Lactobacillus and Bifidobacterium strains, in prevention and treatment of allergic ...
Takashi Shimada +6 more
doaj +1 more source
Chronic helminth infection burden differentially affects haematopoietic cell development while ageing selectively impairs adaptive responses to infection [PDF]
Throughout the lifespan of an individual, the immune system undergoes complex changes while facing novel and chronic infections. Helminths, which infect over one billion people and impose heavy livestock productivity losses, typically cause chronic ...
Babayan, Simon A. +3 more
core +1 more source
The Japanese Macaque as a Diabetes Recipient Animal Model for Porcine Islet Xenotransplantation
Porcine islet xenotransplantation is effective for severe diabetes; however, preclinical studies are essential. In this study, we evaluated the suitability of the Japanese macaque as a recipient model for islet xenotransplantation, including identifying the preferred method to induce diabetes.
Naoaki Sakata +4 more
wiley +1 more source

