Borrelia and Genital Lichen Sclerosus: A Critical Review of the Evidence
JEADV Clinical Practice, EarlyView.ABSTRACT Background Lichen sclerosus (LSc) is a chronic inflammatory dermatosis that primarily affects the genitalia. Growing evidence supports chronic occlusive urine exposure as the principal pathogenic driver, though other mechanisms, including mechanical irritation, hormonal influences, autoimmunity, and infection, have been proposed.
Liang Zhi Wong +4 more
wiley +1 more source
Coexistence of emerging bacterial pathogens in Ixodes ricinus ticks in Serbia*
Parasite, 2010 The list of tick-borne pathogens is long, varied and includes viruses, bacteria, protozoa and nematodes. As all of these agents can exist in ticks, their co-infections have been previously reported.
Tomanović S. +3 more
doaj +1 more source
Investigation of ospC Expression Variation among Borrelia burgdorferi Strains
Frontiers in Cellular and Infection Microbiology, 2017 Outer surface protein C (OspC) is the most studied major virulence factor of Borrelia burgdorferi, the causative agent of Lyme disease. The level of OspC varies dramatically among B.
X. Frank Yang +9 more
doaj +1 more source
mSphere, 2022 Decorin binding protein A (DbpA) is a surface adhesin of Borrelia burgdorferi, the causative agent of Lyme disease. While DbpA is one of the most immunogenic of B.
Elaheh Movahed +7 more
doaj +1 more source
, 2010 Pur-α is a nucleic acid-binding protein involved in cell cycle control, transcription, and neuronal function. Initially no prediction of the three-dimensional structure of Pur-α was possible.
Graebsch, Almut +4 more
core +1 more source
RNA-Seq-based analysis of changes in Borrelia burgdorferi gene expression linked to pathogenicity
Parasites & Vectors, 2015 Background Lyme disease is a global public health problem caused by the spirochaete Borrelia burgdorferi. Our previous studies found differences in disease severity between B. burgdorferi B31- and B. garinii SZ-infected mice.
Qiong Wu +5 more
doaj +1 more source
Robust B Cell Responses Predict Rapid Resolution of Lyme Disease
Frontiers in Immunology, 2018 Lyme disease (Borrelia burgdorferi infection) is increasingly recognized as a significant source of morbidity worldwide. Here, we show that blood plasmablasts and CD27− memory B cells are elevated in untreated Lyme disease, with higher plasmablast levels
Lisa K. Blum +13 more
doaj +1 more source
Disruption of bbe02 by Insertion of a Luciferase Gene Increases Transformation Efficiency of Borrelia burgdorferi and Allows Live Imaging in Lyme Disease Susceptible C3H Mice. [PDF]
PLoS ONE, 2015 Lyme disease is the most prevalent tick-borne disease in North America and Europe. The causative agent, Borrelia burgdorferi persists in the white-footed mouse. Infection with B.
Kamfai Chan +3 more
doaj +1 more source
Variations in Ixodes ricinus Density and Borrelia Infections Associated with Cattle Introduced into a Woodland in The Netherlands [PDF]
, 2008 The effect of introduced large herbivores on the abundance of Ixodes ricinus ticks and their Borrelia infections was studied in a natural woodland in The Netherlands. Oak and pine plots, either ungrazed or grazed by cattle, were selected.
Gassner, F. +5 more
core +2 more sources
‘Reservoir dogs’: The emerging zoonotic risk associated with European dog imports to the UK
Veterinary Record, EarlyView.Abstract Background The movement of dogs from continental Europe to the UK poses a growing public health threat due to the associated risk of disease incursions. Current legislation is insufficient to address the risks and pre‐import control measures are focused only on rabies virus and the fox tapeworm Echinococcus multilocularis. Methods We conducted
Poppy Simonson +2 more
wiley +1 more source