Results 71 to 80 of about 37,097 (225)

DhhP, a Cyclic di-AMP Phosphodiesterase of Borrelia burgdorferi, Is Essential for Cell Growth and Virulence [PDF]

, 2014
Cyclic di-AMP (c-di-AMP) is a recently discovered second messenger in bacteria. Most of work on c-di-AMP signaling has been done in Gram-positive bacteria, firmicutes, and actinobacteria, where c-di-AMP signaling pathways affect potassium transport, cell
Fang, Xin, Gomelsky, Mark, Lawlis, Gavin B., Lou, Yongliang, Troxell, Bryan, Yang, X. Frank, Ye, Meiping, Zhang, Jun-Jie, Zhou, Yan   +8 more
core   +1 more source

Citizen science project on urban canids provides different results from camera traps but generates interest and revenue

Wildlife Biology, EarlyView.
As urbanization increases, wildlife increasingly encounters people. Coyotes Canis latrans and red foxes Vulpes vulpes are two canid species that have readily adapted to urban environments. Citizen science has emerged as a low‐cost method of collecting data on urban‐adapted species that can benefit management agencies but may provide different results ...
Neville F. Taraporevala, Jon P. Beckmann, Julie K. Young   +2 more
wiley   +1 more source

Decorin binding proteins of Borrelia burgdorferi promote arthritis development and joint specific post-treatment DNA persistence in mice. [PDF]

PLoS ONE, 2015
Decorin binding proteins A and B (DbpA and B) of Borrelia burgdorferi are of critical importance for the virulence of the spirochete. The objective of the present study was to further clarify the contribution of DbpA and B to development of arthritis and
Jemiina Salo, Annukka Jaatinen, Mirva Söderström, Matti K Viljanen, Jukka Hytönen   +4 more
doaj   +1 more source

The Borrelia afzelii outer membrane protein BAPKO_0422 binds human Factor-H and is predicted to form a membrane-spanning beta-barrel [PDF]

, 2015
The deep evolutionary history of the Spirochetes places their branch point early in the evolution of the diderms, before the divergence of the present day Proteobacteria.
Adam Dyer, Albrecht, Bagos, Barcena-Uribarri, Behera, Bhide, Bordier, Brooks, Bunikis, Cabello, Casjens, Coutte, Crago, Crother, Cullen, Di, Dietrich, Eddy, Eswar, Fairman, Feng, Finn, Fraser, Freeman, Gemma Brown, Gessmann, Greene, Guina, Heffernan, Hong, Jaroszewski, Kenedy, Koebnik, Kopp, Kraiczy, Kurtenbach, Lenhart, Lenka Stejskal, Livengood, Margos, Mertins, Mittal, Nair, Oksi, Ornstein, Ostberg, Paetzel, Pautsch, Petersen, Peter R. Laity, Pettersen, Prasadarao, Preac-Mursic, Pugsley, Pulzova, Richard J. Bingham, Robert, Rogovskyy, Schmidli, Schulz, Setubal, Skare, Sperisen, Steere, Struyve, Sugawara, Svergun, Tamm, Thein, Tilly, Tommassen, Vogt, Volkov, Xie, Yamashita, Yang, Zhang   +76 more
core   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, EarlyView.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source

Investigating BB0405 as a novel Borrelia afzelii vaccination candidate in Lyme borreliosis

Scientific Reports, 2021
BB0405 is a surface exposed Borrelia burgdorferi protein and its vaccination protected mice against B. burgdorferi infection. As BB0405 is highly conserved across different B.
M. J. Klouwens, J. J. Trentelman, J. I. Ersoz, F. Nieves Marques Porto, R. Sima, O. Hajdusek, M. Thakur, U. Pal, J. W. Hovius   +8 more
doaj   +1 more source

Cellular immune response of Amblyomma sculptum and Amblyomma americanum to entomopathogenic fungi: Implications for biological tick control

Medical and Veterinary Entomology, EarlyView.
Amblyomma sculptum showed a plasmatocyte‐dominant haemocyte profile. Beauveria bassiana increased plasmatocytes and reduced granulocytes, whereas Metarhizium robertsii did not cause significant changes. Amblyomma americanum showed a granulocyte‐dominant haemocyte profile. Beauveria bassiana reduced total haemocytes and granulocytes. B.
Cárita de Souza Ribeiro‐Silva, Valesca Henrique Lima, Salorrane Miranda N. Pinto, Gustavo Felizardo S. Sandes, Victor Hugo Ribeiro Costa, Albert Mulenga, Adela S. Oliva Chavez, Éverton Kort Kamp Fernandes   +7 more
wiley   +1 more source

Differences in clinicopathologic variables between Borrelia C6 antigen seroreactive and Borrelia C6 seronegative glomerulopathy in dogs. [PDF]

, 2019
BackgroundRapidly progressive glomerulonephritis has been described in dogs that seroreact to Borrelia burgdorferi, but no studies have compared clinicopathologic differences in Lyme-seroreactive dogs with protein-losing nephropathy (PLN) versus dogs ...
Goldstein RE, Grauer GF, Kalish RA, Levy S, Levy SA, Rolla D, Scorpio DG   +6 more
core   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Borrelia burgdorferi sensu lato inhibits CIITA transcription through pSTAT3 activation and enhanced SOCS1 and SOCS3 expression leading to limited IFN-γ production

Ticks and Tick-Borne Diseases
Interferons (IFNs) are important signaling molecules in the human immune response against micro-organisms. Throughout initial Borrelia burgdorferi sensu lato (B.
Michelle A.E. Brouwer, Zara Karami, Samuel T. Keating, Hedwig Vrijmoeth, Heidi L.M. Lemmers, Helga Dijkstra, Frank L. van de Veerdonk, Mihaela Lupse, Hadewych J.M. ter Hofstede, Mihai G. Netea, Leo A.B. Joosten   +10 more
doaj   +1 more source