Results 71 to 80 of about 362,885 (283)

On Fodor on Darwin on Evolution [PDF]

open access: yes, 2009
Jerry Fodor argues that Darwin was wrong about "natural selection" because (1) it is only a tautology rather than a scientific law that can support counterfactuals ("If X had happened, Y would have happened") and because (2) only minds can select.
Harnad, Stevan
core   +1 more source

Numerical Simulations of Turbulent Molecular Clouds Regulated by Radiation Feedback Forces II: Radiation-Gas Interactions and Outflows

open access: yes, 2016
Momentum deposition by radiation pressure from young, massive stars may help to destroy molecular clouds and unbind stellar clusters by driving large-scale outflows. We extend our previous numerical radiation hydrodynamic study of turbulent, star-forming
Ostriker, Eve C.   +2 more
core   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

A influência de eventos antecedentes nos problemas de comportamento infantil: revisão de conceitos e aplicabilidade

open access: yesInteração em Psicologia, 2011
Considerando o aumento no número de estudos aplicados realizados no exterior e a ausência de publicações brasileiras em Análise do Comportamento que relacionam eventos antecedentes a problemas comportamentais infantis, este artigo objetiva descrever: (1)
Camila Carmo de Menezes   +1 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

B. F. Skinner

open access: yes, 2006
Excerpt: Born in 1904 in Susquehanna, Pennsylvania, and son of a lawyer, B. F. Skinner (1904–90) was raised in a middle-class Protestant family. He attended Hamilton College and planned a literary career, but soon enrolled in *psychology, completing his
Bufford, Rodger K.
core  

A jackknife variance estimator for self-weighted two-stage samples

open access: yes, 2013
Self-weighted two-stage sampling designs are popular in practice as they simplify field-work. It is common in practice to compute variance estimates only from the first sampling stage, neglecting the second stage.
Berger, Y.G., Escobar, E.L.
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Do mecanicismo ao selecionismo: uma breve contextualização da transição do behaviorismo radical

open access: yesPsicologia: Teoria e Pesquisa
O behaviorismo radical, como filosofia da ciência do comportamento formulada por B. F. Skinner, tem sido desde sua criação alvo de inúmeras críticas e tentativas de rotulação.
Robson Nascimento da Cruz   +1 more
doaj   +1 more source

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