Results 31 to 40 of about 2,176,746 (281)

Modulation of Negative Work Output from a Steering Muscle of the Blowfly Calliphora Vicina [PDF]

, 1994
Of the 17 muscles responsible for flight control in flies, only the first basalar muscle (b1) is known to fire an action potential each and every wing beat at a precise phase of the wing-beat period.
Dickinson, Michael H., Tu, Michael S.
core  

Universal phase transitions of B1 structured stoichiometric transition-metal carbides

, 2011
The high-pressure phase transitions of B1-structured stoichiometric transition metal carbides (TMCs, TM=Ti, Zr, Hf, V, Nb, and Ta) were systematically investigated using ab initio calculations.
Ahuja R., Bo Xu, Cohen A. J., De Vita A., Dubrovinskaia N. A., Gao G. Y., Gao G. Y., Glass C. W., Guo Q. Z., Habas M. -P., Hui-Tian Wang, Jacobsen S. D., Julong He, Kresse G., Kusaba K., Li Q., Li Y. W., Li-Min Wang, Liermann H. P., Liermann H. P., Liermann H. P., Lv J., Ma Y. M., Ma Y. M., Mao H. K., Mehl M. J., Monkhorst H. J., Nye J. F., Oganov A. R., Oganov A. R., Oganov A. R., Oganov A. R., Ono S., Pendas A. M., Perdew J. P., Rousse G., Shoji H., Stokes H. T., Stokes H. T., Toledano P., Vanderbilt D., Wang Y. C., Watanabe M., Winkler B., Xiang-Feng Zhou, Xie Y., Xu J. A., Yongjun Tian, Yoo C. S., Zhang M. G., Zhisheng Zhao, Zhongyuan Liu   +51 more
core   +1 more source

The CHESS chemical Herschel surveys of star forming regions: Peering into the protostellar shock L1157-B1. I. Shock chemical complexity [PDF]

, 2010
We present the first results of the unbiased survey of the L1157-B1 bow shock, obtained with HIFI in the framework of the key program Chemical Herschel surveys of star forming regions (CHESS).
A. Bacmann, A. Baudry, A. Boogert, A. Castets, A. Coutens, A. Fuente, A. Klotz, A. Lorenzani, A. Walters, B. Larsson, B. Lefloch, B. Nisini, B. Parise, Bachiller, Bachiller, Benedettini, C. Borys, C. Ceccarelli, C. Codella, C. Comito, C. Dominik, C. Kahane, C. Kramer, C. Vastel, Codella, D. Lis, D. Neufeld, Davis, de Graauw, E. A. Bergin, E. Caux, E. Falgarone, E. Herbst, F. Gueth, F. Helmich, F. van der Tak, F. Wyrowski, G. Blake, G. Melnick, Garay, Goldsmith, Gueth, Gueth, Gusdorf, H. Yorke, I. Mehdi, J. Cernicharo, J. Pearson, J. Stutzki, Jiménez-Serra, Jørgensen, K. Demyk, K. Schuster, L. Pagani, Lefloch, Looney, M. Benedettini, M. Gerin, M. Kama, M. Salez, M. van der Wiel, Müller, N. Crimier, Neufeld, Nisini, P. Caselli, P. Encrenaz, P. Goldsmith, P. Hennebelle, P. Hily-Blant, P. Saraceno, P. Schilke, Pickett, Pilbratt, Pottage, S. Bottinelli, S. Cabrit, S. Lord, S. Maret, S. Pacheco, S. Viti, Schöier, T. Bell, T. Jacq, T. Phillips, Th. Henning, V. Ossenkopf, V. Wakelam, Van der Tak, van Dishoeck, Viotti, W. Langer, X. Tielens, Y. Delorme   +93 more
core   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Targeted Treatment of Metastatic Triple-Negative Breast Cancer: A Systematic Review

The Breast Journal
Introduction. Triple-negative breast cancer (TNBC) is a subgroup of breast cancer characterized by the absence of estrogen and the human epidermal 2 receptor and also a lack of targeted therapy options.
Anna Martha Hammershøi Madsen, Rikke Helene Løvendahl Eefsen, Dorte Nielsen, Iben Kümler   +3 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Selective One-Pot Multicomponent Synthesis of N-Substituted 2,3,5-Functionalized 3-Cyanopyrroles via the Reaction between α-Hydroxyketones, Oxoacetonitriles, and Primary Amines

Molecules, 2022
A one-step, three-component reaction between α-hydroxyketones, oxoacetonitriles, and primary amines gives N-substituted 2,3,5-functionalized 3-cyanopyrroles with complete selectivity in up to 90% isolated yields.
Mengxin Xia, Ziad Moussa, Zaher M. A. Judeh   +2 more
doaj   +1 more source

Experiments on the carboxylase of pea roots [PDF]

, 1941
It is known that vitamin B1 is a growth factor for numerous bacteria and fungi including the yeasts (see the summary in Koser and Saunders (1938)). It has also been demonstrated that vitamin B1 is essential for the growth of the isolated roots of higher ...
Heegaard, Erik, Horowitz, N. H.
core  

Current status and future directions of botulinum neurotoxins for targeting pain processing. [PDF]

, 2015
Current evidence suggests that botulinum neurotoxins (BoNTs) A1 and B1, given locally into peripheral tissues such as skin, muscles, and joints, alter nociceptive processing otherwise initiated by inflammation or nerve injury in animal models and humans.
Pellett, Sabine, Ramachandran, Roshni, Yaksh, Tony L   +2 more
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source