Results 51 to 60 of about 2,176,746 (281)

Reciprocal knock-in mice to investigate the functional redundancy of lamin B1 and lamin B2. [PDF]

open access: yes, 2014
Lamins B1 and B2 (B-type lamins) have very similar sequences and are expressed ubiquitously. In addition, both Lmnb1- and Lmnb2-deficient mice die soon after birth with neuronal layering abnormalities in the cerebral cortex, a consequence of defective ...
Coffinier, Catherine   +10 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Describing a1 and b1 decays

open access: yes, 1999
Two-body pion-radiating and weak decays of light axial-vector mesons and the rho are studied as a phenomenological application of the QCD Dyson-Schwinger equations. Models based on the rainbow-ladder truncation are capable of providing a good description
Bloch, J. C. R.   +3 more
core   +1 more source

A proanthocyanidin from cinnamomum zeylanicum stimulates phosphorylation of insulin receptor in 3t3-l1 adipocytes [PDF]

open access: yes, 2006
Non-insulin-dependent diabetes mellitus is due to in large part to insulin resistance, a state where the target cells are no longer responding to ordinary levels of circulating insulin.
Abdul Majid, Fadzilah Adibah   +2 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Bayesian clinical trial designs : Another option for trauma trials? [PDF]

open access: yes, 2017
The UK-REBOA Trial is funded by the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme (project number 14/199/09). PP was supported by the MRC Network of Hubs for Trials Methodology Research (MR/L004933/1-R/N/P/B1).
Campbell, Marion K.   +4 more
core   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Photo-realistic traffic scene datasets: real and synthetic perspectives for vision-based analysisMendeley Data

open access: yesData in Brief
Perception plays a crucial role in autonomous driving and computer vision, particularly in interpreting traffic scenes from monocular cameras. In this article, we present a comprehensive collection of traffic scene datasets organized into four distinct ...
Khulan Khalzaa   +3 more
doaj   +1 more source

Distribution records and extended range of the Sri Lanka Frogmouth Batrachostomus moniliger (Aves: Caprimulgiformes: Podargidae) in the Western Ghats: a review from 1862 to 2015

open access: yesJournal of Threatened Taxa, 2016
The Sri Lanka Frogmouth (or Ceylon Frogmouth) Batrachostomus moniliger is an endemic resident bird confined to the evergreen and secondary forests of Sri Lanka and the Western Ghats of India.
Anil Mahabal   +2 more
doaj   +1 more source

Dysregulation of of phospholipid-specific phagocytosis by B1 B cells in diet-induced obese mice [PDF]

open access: yes, 2016
B1 B cells have received increasing attention recently due to their newly discovered phagocytic and microbicidal capabilities. Several studies have demonstrated that B1 cells can phagocytize polystyrene fluorescent particles, bacteria (Staphylococcus ...
Vo, Hung
core   +1 more source

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