Results 41 to 50 of about 422,420 (292)

Association of serum Magnesium levels with renal function in patients with diabetes mellitus type 2. A cross sectional study in rural population of North Telangana [PDF]

open access: yesPerspectives In Medical Research, 2018
Introduction: Diabetes mellitus is one of the most common metabolic disorder and leading cause of death and disability in the world. Magnesium deficiency can lead to development of diabetic complications such as nephropathy, retinopathy, thrombosis ...
Kishan Reddy H1 , Venugopal B2
doaj  

Synergistic Activity of Nitroimidazole-Oxazolidinone Conjugates against Anaerobic Bacteria

open access: yesMolecules, 2020
The introductions of the bicyclic 4-nitroimidazole and the oxazolidinone classes of antimicrobial agents represented the most significant advancements in the infectious disease area during the past two decades.
Zhijun Zhuang   +13 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Tobacco Products Directive - new opportunities for EU tobacco control

open access: yesTobacco Prevention and Cessation, 2016
The Tobacco Products Directive 2014/40/EU was adopted in 2014 and needs to be transposed by Member States by 20 May 2016. It sets out ambitious tobacco control measures in the areas of ingredients, packaging & labelling, electronic cigarettes and ...
Anna-Eva Ampelas
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Porcine Single-Eye Retinal Pigment Epithelium Cell Culture for Barrier and Polarity Studies

open access: yesCells
Age-related macular degeneration (AMD) is the main cause of blindness in Western nations. AMD models addressing specific pathological pathways are desired.
Philipp Dörschmann   +4 more
doaj   +1 more source

Analysis of Polarization and Depolarization Currents of Samples of NOMEX®910 Cellulose–Aramid Insulation Impregnated with Mineral Oil

open access: yesEnergies, 2020
The article presents results of laboratory tests performed on samples of NOMEX®910 cellulose–aramid insulation impregnated with Nynas Nytro 10× inhibited insulating mineral oil using the polarization and depolarization current analysis method (PDC Method)
Stefan Wolny, Adam Krotowski
doaj   +1 more source

B2-InF Step by Step

open access: yes, 2021
The three main steps of the project are fully detailed in this blog ...
B2-InF Consortium
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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