Results 61 to 70 of about 384,635 (297)

Single-Eye Porcine Retinal Pigment Epithelium Cell Cultures—A Validated and Reproducible Protocol

open access: yesBioMed
Background: Age-related macular degeneration (AMD) is the leading cause of severe vision loss in industrialized nations. AMD models based on standardized optimized cell culture models are warranted.
Philipp Dörschmann   +4 more
doaj   +1 more source

On Motivation to Apply ODL in Adult Teachers' Education

open access: yesInformatics in Education, 2011
This paper investigates the motivation of teachers of primary education to be trained by means of ODL (Open and Distance Learning). The survey took place during a professional training period and aimed to investigate initially the awareness of the ...
Athanasis KAROULIS
doaj   +1 more source

Study of Mono- and Bimetallic Fe and Mn Oxide-Supported Clinoptilolite for Improved Pb(II) Removal

open access: yesMolecules, 2021
A cost-effective, iron- and manganese-oxide-supported clinoptilolite-based rock was prepared. Based on its nanoporous structure, it worked as a nanoreactor, thereby providing enhanced functionalities.
Eva Chmielewská   +2 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Expression of chicken lamin B2 in Escherichia coli : characterization of its structure, assembly, and molecular interactions [PDF]

open access: yes, 1991
Chicken lamin B2, a nuclear member of the intermediate-type filament (IF) protein family, was expressed as a full-length protein in Escherichia coli.
Aebi, U.   +11 more
core   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Kinin-B1 receptors in ischaemia-induced pancreatitis: Functional importance and cellular localisation [PDF]

open access: yes, 2003
In this study we compare the role of kininB1 and B2 receptors during ischaemia/reperfusion of rat pancreas. Our investigations were prompted by the observation that infusion of a kininB2 receptor antagonist produced significant improvement in acute ...
A. A. Roscher   +11 more
core   +1 more source

Fucoidan from Fucus vesiculosus Protects Retinal Pigment Epithelium from Lipid-Induced Damage Related to AMD

open access: yesMarine Drugs
Fucoidans are natural compounds that exhibit bioactivity against age-related macular degeneration (AMD), the leading cause of central vision loss in industrialized nations.
Femke Hacker   +3 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

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