Results 291 to 300 of about 31,066,857 (388)

Multidisciplinary Management of Paraneoplastic Pemphigus Associated with B-Cell Lymphoma: A Case Report. [PDF]

Int Med Case Rep J
Alothman L, Bin Mubayrik A, Alfurayh N, Aldosary S, Alotaibi HM, Alajlan A.   +5 more
europepmc   +1 more source

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

Nature, 2010
R. Davis, V. Ngo, G. Lenz, P. Tolar, R. Young, Paul B. Romesser, H. Kohlhammer, L. Lamy, Hong Zhao, Yandan Yang, Weihong Xu, A. Shaffer, George W. Wright, Wenming Xiao, J. Powell, Jian-Kang Jiang, Craig J. Thomas, A. Rosenwald, G. Ott, H. Müller-hermelink, R. Gascoyne, J. Connors, N. Johnson, L. Rimsza, E. Campo, E. Jaffe, W. Wilson, J. Delabie, E. Smeland, R. Fisher, R. Braziel, R. Tubbs, J. Cook, D. Weisenburger, W. C. Chan, S. Pierce, L. Staudt   +36 more
semanticscholar   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Shared genomic features of HIV+ diffuse large B-cell lymphoma in two African cohorts. [PDF]

Sci Rep
Roush SM, Moodley M, Coelho J, Beck S, Chirwa A, Kasonkanji E, Mponda M, Mulenga M, Tomoka T, van Zijl H, Hodkinson K, Ismail A, Mtshali S, Featherston J, Gopal S, Painschab MS, Vaughan J, Fedoriw Y.   +17 more
europepmc   +1 more source

Single-Cell Trajectory Detection Uncovers Progression and Regulatory Coordination in Human B Cell Development

Cell, 2014
S. Bendall, K. Davis, E. Amir, Michelle D. Tadmor, Erin F. Simonds, Tiffany J. Chen, Daniel K. Shenfeld, G. Nolan, D. Pe’er   +8 more
semanticscholar   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Mutational signatures and kataegis in pediatric B-cell precursor acute lymphoblastic leukemia. [PDF]

Hemasphere
Gunnarsson R, Yang M, Biloglav A, Lundin-Ström KB, Lilljebjörn H, Castor A, Fioretos T, Olsson-Arvidsson L, Paulsson K, Johansson B.   +9 more
europepmc   +1 more source

Neonatally Induced Tolerance to HGG: Duration in B Cells and Absence of Specific Suppressor Cells

, 1977
David C. Benjamin
openalex   +1 more source