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CD5 B Cells, a Fetal B Cell Lineage
1993Publisher Summary This chapter presents a short background of CD5 expression on B cells and focuses on the issue of the relationship of CD5 B cells to B cell development, proposing a model that views this subset as the progeny of a fetal B cell differentiation pathway.
Richard R. Hardy, Kyoko Hayakawa
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2020
B cells are typically characterized by their ability to produce antibodies, function as secondary antigen-present cells, and produce various immunoregulatory cytokines. The regulatory B (Breg)-cell population is now widely accepted as an important modulatory component of the immune system that suppresses inflammation.
Yiwei Chu, Ying Fu, Luman Wang
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B cells are typically characterized by their ability to produce antibodies, function as secondary antigen-present cells, and produce various immunoregulatory cytokines. The regulatory B (Breg)-cell population is now widely accepted as an important modulatory component of the immune system that suppresses inflammation.
Yiwei Chu, Ying Fu, Luman Wang
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Immunology Today, 1991
Abstract In this article Jose Ales-Martinez and colleagues explore the role of Ig-associated molecules in providing isotype specificity to signals triggered by receptor crosslinking, focusing on possible differences between immature and mature B cells.
R.M.E. Parkhouse +5 more
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Abstract In this article Jose Ales-Martinez and colleagues explore the role of Ig-associated molecules in providing isotype specificity to signals triggered by receptor crosslinking, focusing on possible differences between immature and mature B cells.
R.M.E. Parkhouse +5 more
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Blood, 2010
In this issue of Blood , Isnardi and colleagues describe a phenotypically distinct population of autoreactive B cells that have become functionally limited upon stimulation, or “anergic.”[1][1] Importantly, these cells are found at increased frequency in some rheumatoid arthritis patients and ...
Sarah F. Andrews, Patrick C. Wilson
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In this issue of Blood , Isnardi and colleagues describe a phenotypically distinct population of autoreactive B cells that have become functionally limited upon stimulation, or “anergic.”[1][1] Importantly, these cells are found at increased frequency in some rheumatoid arthritis patients and ...
Sarah F. Andrews, Patrick C. Wilson
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B-cell receptor regulation of peripheral B cells
Current Opinion in Immunology, 1998Recent studies indicate that immature B cells compete with recirculating B cells for survival signals. The signals, delivered through the B-cell receptor for antigen, induce immature cells to differentiate into recirculating cells and maintain the survival of recirculating cells. They do not induce proliferation or differentiation to antibody-producing
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Current Opinion in Immunology, 1995
Recent studies have identified CD40 ligand (CD40L) as the critical membrane-expressed molecule responsible for T cell dependent B-cell activation. CD40L co-operates with various cytokines to induce B-cell activation, proliferation, and immunoglobulin isotype switching.
Richard J. Armitage, Mark R. Alderson
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Recent studies have identified CD40 ligand (CD40L) as the critical membrane-expressed molecule responsible for T cell dependent B-cell activation. CD40L co-operates with various cytokines to induce B-cell activation, proliferation, and immunoglobulin isotype switching.
Richard J. Armitage, Mark R. Alderson
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T Cell–Dependent B Cell Activation
Annual Review of Immunology, 1993B cells obtain help from T cells in the antibody response by acting as antigen-specific antigen presenting cells. A direct signal through binding of antigen to membrane Ig can enhance B cell antigen presentation and T-dependent B cell activation, but is not required for a productive interaction between a small resting B cell and a differentiated helper
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European Journal of Immunology, 2006
AbstractPriming of naive lymphocytes is important for yielding efficient immune responses. Mechanisms controlling this process are also important for preventing immune cells from attacking self‐antigens. It is well known that signals provided by innate immune receptors, such as Toll‐like receptors (TLR), are essential to induce dendritic cell ...
Rudolf A. Manz, Simon Fillatreau
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AbstractPriming of naive lymphocytes is important for yielding efficient immune responses. Mechanisms controlling this process are also important for preventing immune cells from attacking self‐antigens. It is well known that signals provided by innate immune receptors, such as Toll‐like receptors (TLR), are essential to induce dendritic cell ...
Rudolf A. Manz, Simon Fillatreau
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Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
Nature, 2000Ash A. Alizadeh +30 more
semanticscholar +1 more source
2010
Cellular reprogramming is an interplay between the original starting cell's plasticity and the (epi)genetic mechanisms used to drive this cell towards a new fate. Our capacity to reprogram mature cells into progenitors thus greatly depends on the inherent physiological plasticity of the initial cell.
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Cellular reprogramming is an interplay between the original starting cell's plasticity and the (epi)genetic mechanisms used to drive this cell towards a new fate. Our capacity to reprogram mature cells into progenitors thus greatly depends on the inherent physiological plasticity of the initial cell.
openaire +3 more sources