Results 21 to 30 of about 288,045 (238)

Characterization of antibody-mediated neutralization directed against the hypervariable region 1 of hepatitis C virus E2 glycoprotein [PDF]

, 2010
The hypervariable region 1 (HVR1) comprising the first 27 aa of E2 glycoprotein is a target for neutralizing antibodies against hepatitis C virus (HCV), but the mechanisms of this neutralization in the cell-culture-infectious genotype 2a strain JFH1 ...
Dubuisson, J., J. Dubuisson, A. H. Patel, G. Vieyres, Patel, A.H., Vieyres, G.   +5 more
core   +1 more source

Variation in the organization and subunit composition of the mammalian pyruvate dehydrogenase complex E2/E3BP core assembly [PDF]

, 2011
Crucial to glucose homoeostasis in humans, the hPDC (human pyruvate dehydrogenase complex) is a massive molecular machine comprising multiple copies of three distinct enzymes (E1–E3) and an accessory subunit, E3BP (E3-binding protein). Its icosahedral E2/
Swetha Vijayakrishnan, Byron, Olwyn, Lindsay, J., Gilbert, David, Cooper, Alan, Lindsay, J.G., Nutley, Margaret A, Philip Callow, Byron, O., Callow, P, David Gilbert, Kropholler, P., Callow, Philip, Byron, O, McGow, D., Vijayakrishnan, S, David, Gilbert, Vijayakrishnan, Swetha, McGow, Donna P., Nutley, M.A., Gilbert, D, Callow, P., Kropholler, P, Alan Cooper, Nutley, Margaret A., Cooper, A., Donna P. McGow, Lindsay, J Gordon, Nutley, M., Lindsay, J. Gordon, Cooper, A, J. Gordon Lindsay, Vijayakrishnan, S., McGow, DP, Margaret A. Nutley, Olwyn Byron, Kropholler, Peter, Peter Kropholler, Mcgow, Donna P, Lindsay, JG, Nutley, MA, McGow, D.P., Gilbert, D.   +42 more
core   +1 more source

E2-T179N increases viral replication of MAYV and CHIKV in insect cells and causes early release.

, 2023
A-C: Replication of WT MAYV and MAYV E2-T179N in insect and human cells. Aag2 (A) and U4.4 (B) cells were infected with WT MAYV or MAYV E2-T179N at a MOI of 0.1, while MRC-5 were infected at a MOI of 0.01 (C). Replication was assessed over time by plaque
Rafael Elias Marques (9953951), James Weger-Lucarelli (603766), Thomas Vallet (7847147), Tyler A. Bates (9313466), Hervé Blanc (3561122), Maria-Carla Saleh (334367), Ferdinand Roesch (151634), Marco Vignuzzi (238667), Cassandra Koh (4923757), Lucía Carrau (653832), Jesse D. Bloom (8796629), Annabelle Henrion-Lacritick (10112992), Truitt J. Elliott (12855998), Jeffrey M. Marano (15188350), Shamima Akter (586551), Chelsea Cereghino (15188341), Christina Chuong (9313463), Alexandra Hardy (15188344), Helder V. Ribeiro-Filho (15188347), Anne M. Brown (1403170), Tanya LeRoith (4247656), Pallavi Rai (15188353), Pawel Michalak (33549)   +22 more
core   +1 more source

Sequence analysis of Epstein-Barr virus EBNA-2 gene coding amino acid 148-487 in nasopharyngeal and gastric carcinomas

Virology Journal, 2012
Background The Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA-2) plays a key role in the B-cell growth transformation by initiating and maintaining the proliferation of infected B-cell upon EBV infection in vitro. Most studies about EBNA-2 have focused
Wang Xinying, Wang Yun, Wu Guocai, Chao Yan, Sun Zhifu, Luo Bing   +5 more
doaj   +1 more source

E2-T179N attenuates MAYV replication and tissue pathology in mice.

, 2023
Four-week-old CD-1 mice were infected with 105 PFU in 50 μL via injection to the left, hind footpad. A: Viral load in serum was assessed daily by plaque assay. Statistical comparisons were made using multiple unpaired t tests with correction for multiple
Rafael Elias Marques (9953951), James Weger-Lucarelli (603766), Thomas Vallet (7847147), Tyler A. Bates (9313466), Hervé Blanc (3561122), Maria-Carla Saleh (334367), Ferdinand Roesch (151634), Marco Vignuzzi (238667), Cassandra Koh (4923757), Lucía Carrau (653832), Jesse D. Bloom (8796629), Annabelle Henrion-Lacritick (10112992), Truitt J. Elliott (12855998), Jeffrey M. Marano (15188350), Shamima Akter (586551), Chelsea Cereghino (15188341), Christina Chuong (9313463), Alexandra Hardy (15188344), Helder V. Ribeiro-Filho (15188347), Anne M. Brown (1403170), Tanya LeRoith (4247656), Pallavi Rai (15188353), Pawel Michalak (33549)   +22 more
core   +1 more source

$B(E2; 2_1^+ \to 0_1^+)$ value in $^{90}Kr$ [PDF]

, 2014
International audienceA smooth onset of collectivity in Kr-88,Kr-92,Kr-94,Kr-96 has been determined from reported B(E2; 2(1)(+) -> 0(1)(+)) and E(2(1)(+)) values. This is in contrast to the sudden onset in even-even Zr, Mo, and Sr isotopes. Our objective
Soldner, T., Fraile, L. M., Bruce, Alison; id_orcid, de France, G, Saed-Samii, N., Ignatov, A., Olaizola, B, Smith, J. F., Vancraeyenest, A, Zielińska, M., Carroll, R, Jentschel, M, Warr, N., Drouet, F, Thuerauf, M, Podolyák, Zs., Bruce, A. M., Clement, E, Lalkovski, S, Ghita, DG, Smith, JF, Mărginean, N., Astier, A., Soldner, T, Leguillon, R., Fraile, LM, Ur, C. A., Stezowski, O, Jolie, J., Mach, H., Ur, C.A., Larijani, C., Warr, N, Blanc, A, Paziy, V., Mutti, P., Astier, A, Hartig, A.-L., Jolie, J, Ilieva, S, Roberts, Oliver, Ur, CA, Marginean, N, Wilson, E., Simpson, G.S., Larijani, C, Koester, U, Salsac, M-D, Ignatov, A, Paziy, V, Regan, PH, Vedia, V., Townsley, C, Roberts, O. J., Kisyov, S, Urban, W., Regan, P.H., Petrache, C.M., Lalkovski, S., Ivanova, D, Petrache, CM, Hartig, A-L, Blanc, A., Köster, U., Regan, P. H., Podolyak, Z, Fraile, L.M., Kröll, T., Leguillon, R, Kroell, T, Thürauf, M., Pfeiffer, M., de France, G., Stezowski, O., Salsac, M.-D., Jentschel, M., Carroll, R., Régis, J.-M., Clément, E., Simpson, GS, Ghită, D., Korten, W., Townsley, C., Lică, R., Petrache, C. M., Olaizola, B., Mutti, P, Smith, J.F., Roberts, OJ, Ivanova, D., Lica, R, Vedia, V, Saed-Samii, N, Bruce, AM, Ilieva, S., Pfeiffer, M, Ghită, D. G., Wilson, E, Mach, H, Kisyov, S., Drouet, F., Zielinska, M, Vancraeyenest, A., Korten, W, Regis, J-M, Urban, W   +105 more
core   +2 more sources

Gynecomastia: Etiological Analysis Beyond Hormonal Imbalance

Life
Background: Gynecomastia is a benign enlargement of the male breast with multiple causes. This retrospective study evaluated whether serum estradiol (E2), testosterone (T), or the E2/T ratio differed between patients and controls, while explicitly ...
Jae Heon Kim, Miho Song, Kisoo Lee, Min Hyuk Lee, Yun Seob Song   +4 more
doaj   +1 more source

Direct regulation of aromatase B expression by 17β-estradiol and dopamine D1 receptor agonist in adult radial glial cells

Frontiers in Neuroscience, 2016
Aromatase cytochrome P450arom (cyp19) is the only enzyme that has the ability to convert androgens into estrogens. Estrogens, which are produced locally in the vertebrate brain play many fundamental roles in neuroendocrine functions, reproductive ...
Lei eXing, Crystal eEsau, Vance L Trudeau   +2 more
doaj   +1 more source

lemmingA encodes the Apc11 subunit of the APC/C in Drosophila melanogaster that forms a ternary complex with the E2-C type ubiquitin conjugating enzyme, Vihar and Morula/Apc2 [PDF]

, 2012
Background: Ubiquitin-dependent protein degradation is a critical step in key cell cycle events, such as metaphase-anaphase transition and mitotic exit.
Udvardy Andor, Deák Péter, Imre Boros, Nagy Olga, Olga Nagy, Margit Pál, Deak, Peter, Boros, Imre, Shirras Alan D, Alan D Shirras, Péter Deák, Nagy, Olga, Pál Margit, Shirras, Alan D., Andor Udvardy, Pal, Margit, Udvardy, Andor, Shirras Christine AM, Boros Imre, Christine AM Shirras, Shirras, Christine A. M.   +20 more
core   +1 more source

Chikungunya Virus E2 Structural Protein B-Cell Epitopes Analysis

Viruses, 2022
The Togaviridae family comprises a large and diverse group of viruses responsible for recurrent outbreaks in humans. Within this family, the Chikungunya virus (CHIKV) is an important Alphavirus in terms of morbidity, mortality, and economic impact on ...
João Paulo da Cruz Silva, Marielton dos Passos Cunha, Shahab Zaki Pour, Vitor Renaux Hering, Daniel Ferreira de Lima Neto, Paolo Marinho de Andrade Zanotto   +5 more
doaj   +1 more source