Results 61 to 70 of about 1,380,427 (248)

Effects of different physiological levels of estradiol on chemosensitivity of HR+ breast cancer in vitro and in vivo

Di-san junyi daxue xuebao, 2020
Objective To investigate the effects of different phases of menstrual cycle or different physiological levels of estradiol (E2) on the chemosensitivity of breast cancer cells and bearing nude mice to epirubicin (EPI).
LIU Jiashuo, XU Zhou, KONG Lingquan, ZOU Baoshan, LI Hao   +4 more
doaj   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou, Carl D. Langefeld, Padmini Sekar, Mary Comeau, Timothy Howard, Tamara N. Kimball, Chen Bowang, Hyacinth I. Hyacinth, Jonathan Rosand, Christopher D. Anderson, Caspar Grond‐Ginsbach, Daniel Woo, Stacie L. Demel   +12 more
wiley   +1 more source

Low-lying states in even Gd isotopes studied with five-dimensional collective Hamiltonian based on covariant density functional theory

, 2018
Five-dimensional collective Hamiltonian based on the covariant density functional theory has been applied to study the the low-lying states of even-even $^{148-162}$Gd isotopes. The shape evolution from $^{148}$Gd to $^{162}$Gd is presented.
Chen, Q. B., Shi, Z., Zhang, S. Q.
core   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro, María Victoria Zelaya, Hasier Eraña, Javier Sánchez Ruiz de Gordoa, Fermín García‐Amigot, Anika Simonovska‐Serra, María Cristina Caballero, Isidre Ferrer, Ellen Gelpi, Ivonne Jericó, Joaquín Castilla   +10 more
wiley   +1 more source

B(E2), B(Ml) and 8(E2/ Ml) of Pt (A=198 & (Z=78) Isotope Using IBM-1

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
Interacting boson model version one has been used in the present theoretical calculations. The energy levels & their transitions for dynamical  symmetry  0(6),  SU(3),  U(5),  ground-state  band,  Beta­ band, Gamma  band, B(E2), Ot, B(Ml), ,u,gt and
K.S Ibraheim, I TAI-Aiawy, H.T Sulaiman
doaj  

The anomalous quadrupole collectivity in Te isotopes

, 2016
We present systematic calculations on the spectroscopy and transition properties of even-even Te isotopes by using the large-scale configuration interaction shell model approach with a realistic interaction.
Qi, Chong
core   +1 more source

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

Sex-Specific Impact of 17β-Estradiol and Testosterone Levels on Inflammation and Injury in Acute Myocardial Infarction—Preliminary Results

Biomedicines
Background: Estrogens play a protective role during the early stages of life. However, endogenous 17β-estradiol (E2) can accelerate atherosclerosis progression.
Niya E. Semerdzhieva, Adelina D. Tsakova, Vesela V. Lozanova   +2 more
doaj   +1 more source

Evaluation of a Radioreceptor Assay to Assess Exogenous Estrogen Activity in Serum of Patients with Breast Cancer

The International Journal of Biological Markers, 1991
A radioreceptor assay (RRA) for the determination of total estrogen activity, was set up and used to assess the possible presence of exogenous molecules with estrogen activity in serum; a comparison was made with the specific radioimmunoassay (RIA) for ...
D. Di Lorenzo, G. Roggeri, C. Iacobello, S. Belloli, M. Gion, D.T. Za Va, S. Ghielmi, A. Albertini   +7 more
doaj   +1 more source