Results 51 to 60 of about 14,692,425 (274)

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Accuracy of B(E2; 0+ -> 2+) transition rates from intermediate-energy Coulomb excitation experiments

, 2005
The method of intermediate-energy Coulomb excitation has been widely used to determine absolute B(E2; 0+ -> 2+) quadrupole excitation strengths in exotic nuclei with even numbers of protons and neutrons. Transition rates measured with intermediate-energy
A. B. McDonald, A. Bohr, A. Buerger, A. Gade, D. B. Fossan, D. S. Andreev, H. Morinaga, J. M. Cook, K. Alder, O. Hausser, T. Glasmacher, V. M. Khvastunov   +11 more
core   +1 more source

Doublet bands in $^{126}$Cs in the triaxial rotor model coupled with two quasiparticles [PDF]

, 2007
The positive parity doublet bands based on the $\pi h_{11/2}\otimes\nu h_{11/2}$ configuration in $^{126}$Cs have been investigated in the two quasi-particles coupled with a triaxial rotor model.
Meng, J., Qi, B., Wang, S. Y., Zhang, S. Q.   +3 more
core   +2 more sources

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Dihydrotestosterone and 17-Estradiol Enhancement of In Vitro Osteogenic Differentiation of Castrated Male Rat Bone Marrow Mesenchymal Stem Cells (rBMMSCs)

International Journal of Hematology-Oncology and Stem Cell Research, 2019
Background: In vitro impact of dihydrotestosterone (DHT) and 17b-estradiol (E2) in osteogenic differentiation of castrated rat bone marrow mesenchymal stem cells (rBMMSC) still need to be clarified. Materials and Methods: The viability, proliferation and
Faten A.M. Abo-Aziza, A.A. Zaki, Amany S. Amer, Rania A. Lotfy   +3 more
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Does Serum Estradiol Prior to Progesterone Administration in Programmed Frozen Embryo Transfer Cycle Impacts Live Birth Rate: A Prospective Cohort Study

Journal of Human Reproductive Sciences
Background: There is a paucity of data on the optimal threshold of oestradiol (E2) levels required for successful implantation as this is a valid question to be answered, considering that significant number of in vitro fertilisation cycles are deferred ...
Neeta Singh, Bakkireddy Saisree, Neena Malhotra, Supriya Kumari, Reeta Mahey, Nisha, Monika Saini   +6 more
doaj   +1 more source

Intracellular antibody signalling is regulated by phosphorylation of the Fc receptor TRIM21

eLife, 2018
Cell surface Fc receptors activate inflammation and are tightly controlled to prevent autoimmunity. Antibodies also simulate potent immune signalling from inside the cell via the cytosolic antibody receptor TRIM21, but how this is regulated is unknown ...
Claire Dickson, Adam J Fletcher, Marina Vaysburd, Ji-Chun Yang, Donna L Mallery, Jingwei Zeng, Christopher M Johnson, Stephen H McLaughlin, Mark Skehel, Sarah Maslen, James Cruickshank, Nicolas Huguenin-Dezot, Jason W Chin, David Neuhaus, Leo C James   +14 more
doaj   +1 more source

Establishment and comparison of two methods to produce a rat model of mammary gland hyperplasia with hyperprolactinemia

Brazilian Journal of Pharmaceutical Sciences, 2022
This study aimed to establish and compare models of mammary gland hyperplasia (MGH) with hyperprolactinemia (HPRL) using two different methods. The models provide information on the relationship between mammary gland hyperplasia and associated hormones ...
Caikui Luo, Yanming Wang, Jili Zou, Jinhu Wu, Junhua Meng, Hanmin Zhou, Yonggang Chen   +6 more
doaj   +1 more source

Astrophysical S-factor of the $^7$Be($p,\gamma)^8$B reaction from Coulomb dissociation of $^8$B

, 1996
The Coulomb dissociation method to obtain the astrophysical S-factor, $S_{17}(0)$, for the $^7$Be($p,\gamma)^8$B reaction at solar energies is investigated by analysing the recently measured data on the breakup reaction $^{208}$Pb$(^8$B,$^7$Be$~p)^{208 ...
A.K. Dutt-Mazumder, Alder, Alexio, Bahcall, Bahcall, Barker, Baur, Baur, Bertulani, Bertulani, Buenerd, Filippone, Filippone, Gai, I.J. Thompson, Kavanagh, Kim, Langanke, Langanke, Langanke, Motobayashi, Nakada, R. Shyam, Rolf, Satchler, Shyam, Tombrello, Turck-Chieze, Typel, Vaughn, Xu   +30 more
core   +2 more sources