Results 61 to 70 of about 288,045 (238)

Abrupt phase change of the core rotation in the 143Sm nucleus

open access: yesPhysics Letters B, 2018
Dipole sequences in the 143Sm nucleus have been investigated via the 124Sn (24Mg, 5n) reaction at Elab = 107 MeV using the Indian National Gamma Array (INGA).
S. Rajbanshi   +12 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Characterization of a Lipoyl Domain-Independent B-Cell Autoepitope on the Human Branched-Chain Acyltransferase in Primary Biliary Cirrhosis and Overlap Syndrome with Autoimmune Hepatitis

open access: yesClinical and Developmental Immunology, 2003
Background and aims: Antimitochondrial antibodies (AMA) which recognize pyruvate acetyltransferase (PDC-E2) represent a highly diagnostic feature of primary biliary cirrhosis (PBC).
Antal Csepregi   +9 more
doaj   +1 more source

ICI 182,780 has agonistic effects and synergizes with estradiol-17 beta in fish liver, but not in testis

open access: yesReproductive Biology and Endocrinology, 2006
Background ICI 182,780 (ICI) belongs to a new class of antiestrogens developed to be pure estrogen antagonists and, in addition to its therapeutic use, it has been used to knock-out estrogen and estrogen receptor (ER) actions in several mammalian species.
Power Deborah M   +5 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Applying Nuclear Shell Model to Study Nuclear Structure for 18Ne by Using OXBASH Code

open access: yesJournal of Kufa-Physics, 2020
In this study, the shell model used to calculate energy levels and reduced electric quadruple transition probability B(E2)  for 18Ne isotope using OXBASH code within the sd shell and using the KUOSD effective interaction.18Ne isotope contain two proton ...
Hadeel H. Abed, Ali k. Hasan
doaj   +1 more source

Identifying the Role of E2 Domains on Alphavirus Neutralization and Protective Immune Responses. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2015
Chikungunya virus (CHIKV) and other alphaviruses are the etiologic agents of numerous diseases in both humans and animals. Despite this, the viral mediators of protective immunity against alphaviruses are poorly understood, highlighted by the lack of a ...
James Weger-Lucarelli   +3 more
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

B(E2), B(Ml) and 8(E2/ Ml) of Pt (A=198 & (Z=78) Isotope Using IBM-1

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
Interacting boson model version one has been used in the present theoretical calculations. The energy levels & their transitions for dynamical  symmetry  0(6),  SU(3),  U(5),  ground-state  band,  Beta­ band, Gamma  band, B(E2), Ot, B(Ml), ,u,gt and
K.S Ibraheim, I TAI-Aiawy, H.T Sulaiman
doaj  

Versatile vector tools for efficient protein screening across multiple expression systems

open access: yesFEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu   +5 more
wiley   +1 more source

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