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B Lymphocytes and the Skeleton

Annals of the New York Academy of Sciences, 2007
Abstract:  Mesenchymal lineage cells arise from pluripotent stem cells in the bone marrow (BM) and transition through a series of developmental stages resulting in mature functional cells. This specification results in the development of osteoblast, adipocytes, myoblasts, chondroblasts, and stromal cells (part of the recticular network).
Mark C, Horowitz, Joseph A, Lorenzo
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B-lymphocyte subpopulations

Immunology Today, 1983
B lymphocytes are exceptionally diverse, partly because different clones have membrane receptors with specificities for different antigens and partly because the cells exist in a series of distinct differentiation states and may constitute more than a single cellular lineage.
J T, Kung, W E, Paul
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Suppressor B lymphocytes

Immunology Today, 1983
B cells can influence an immune response in an antigen-specific manner by generating antibody which shuts down the response through negativefeedback. But there is growing evidence that B cells can also act upon antibody production as non-specific suppressor cells.
K M, Gilbert, M K, Hoffmann
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Interleukins for B lymphocytes

Survey of Immunologic Research, 1983
The above reviews our developing knowledge on the nature of B cell-specific interleu-kins. It may be anticipated that in the next several years, considerable progress will be made in understanding the physicochemical properties of these factors, their time and nature of action, and the nature of their receptors.
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T-lymphocyte function in B-cell chronic lymphocytic leukemia

Clinical Immunology and Immunopathology, 1980
Summary. B‐enriched lymphocyte populations from patients with chronic lymphocytic leukaemia (CLL) were compared to B‐enriched lymphocyte populations from normal age‐matched controls for their ability to stimulate a proliferative response and to generate cytotoxic cells in allogeneic mixed lymphocyte cultures (MLC).
J A, Wolos, F R, Davey
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The nature of the B lymphocyte in B-chronic lymphocytic leukemia.

Blood cells, 1993
We have analyzed phenotypic, functional, and molecular properties of B-chronic lymphocytic leukemia (B-CLL) cells as compared to normal B cell differentiation stages and/or subsets. The possibility that the target B cell population transformed by the I primary oncogenic event(s) belongs to the normal CD5+ B cell subset from B mantle zone of secondary ...
Caligaris Cappio F   +8 more
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B-Lymphocyte Malignancy

New England Journal of Medicine, 1973
The division of the lymphoid system into two major functionally distinct kinds of cells has increased immensely understanding not only of normal immunity but also of neoplasia affecting these cells. It is now abundantly clear that certain lymphocytes are conditioned by the thymus (hence their designation as T-cells) and acquire the ability to mediate ...
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B lymphocyte activation

Immunology Today, 1981
A review focussing on the lessons learned from polyclonal activation of B cells.
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