Results 101 to 110 of about 13,560,698 (307)

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

open access: yesFEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Electromigration-induced resistance switching in indented Al microstrips

open access: yesNew Journal of Physics, 2019
Non-volatile resistive memory cells are promising candidates to tremendously impact the further development of Boolean and neuromorphic computing. In particular, nanoscale memory-bit cells based on electromigration (EM)-induced resistive switching in ...
J Lombardo   +5 more
doaj   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Inclusive and differential cross section measurements of t t ¯ b b ¯ $$ \textrm{t}\overline{\textrm{t}}\textrm{b}\overline{\textrm{b}} $$ production in the lepton+jets channel at s $$ \sqrt{s} $$ = 13 TeV

open access: yesJournal of High Energy Physics
Measurements of inclusive and normalized differential cross sections of the associated production of top quark-antiquark and bottom quark-antiquark pairs, t t ¯ b b ¯ $$ \textrm{t}\overline{\textrm{t}}\textrm{b}\overline{\textrm{b}} $$ , are presented ...
The CMS collaboration   +2362 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Measurement of the Higgs boson production via vector boson fusion and its decay into bottom quarks in proton-proton collisions at s $$ \sqrt{s} $$ = 13 TeV

open access: yesJournal of High Energy Physics
A measurement of the Higgs boson (H) production via vector boson fusion (VBF) and its decay into a bottom quark-antiquark pair ( b b ¯ $$ \textrm{b}\overline{\textrm{b}} $$ ) is presented using proton-proton collision data recorded by the CMS experiment ...
The CMS collaboration   +2325 more
doaj   +1 more source

Imprints of new physics operators in the semileptonic B→a1(1260)ℓ−ν¯ℓ process in SMEFT approach

open access: yesPhysics Letters B
At present, there are several measurements of B decays that exhibit discrepancies with the predictions of the Standard Model, and suggest the presence of new physics in b→s and b→c(u) quark level transitions.
Manas Kumar Mohapatra   +2 more
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

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