Results 61 to 70 of about 13,560,698 (307)
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Theory Status - Puzzles in B Meson Decays and LFU?
SciPost Physics Proceedings, 2019 Currently B meson puzzles motivate many studies of New Physics due to the observed deviations from the Standard Model predictions. There are two B meson puzzles, RD(∗) and RK(∗).
Svjetlana Fajfer
doaj +1 more source
Spectral Verification of the Mechanisms behind FBG-Based Ultrasonic Guided Wave Detection
Sensors, 2020 Ultrasonic guided wave (UGW) detection with fiber Bragg grating (FBG)-based sensors has received increasing attention in the last decades due to the ability to perform non-destructive inspection (NDI) of large plate-like surfaces with a network of ...
Sidney Goossens +2 more
doaj +1 more source
Hematopoietic (stem) cells—The elixir of life?
FEBS Letters, EarlyView.The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
First-Principles Study of the Contact Resistance at 2D Metal/2D Semiconductor Heterojunctions
Applied Sciences, 2020 The high contact resistance at metal/two-dimensional (2D) semiconductor junctions is a major issue for the integration of 2D materials in nanoelectronic devices.
Michel Houssa +3 more
doaj +1 more source
Fingerprinting CP-violating New Physics with B → Kμ + μ −
Journal of High Energy Physics, 2023 The B → Kℓ + ℓ − system is particularly interesting to explore physics beyond the Standard Model. Such effects could provide new sources of CP violation, thereby giving rise to Wilson coefficients which could not only be real, as assumed in most analyses,
Robert Fleischer +3 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The LHCb Simulation Application, Gauss: Design, Evolution and Experience
, 2011 The LHCb simulation application, Gauss, is based on the Gaudi framework and on experiment basic components such as the Event Model and Detector Description.
M. Clemencic +6 more
semanticscholar +1 more source