Results 71 to 80 of about 3,358,361 (284)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
New physics upper bound on the branching ratio of B_s --> l+ l-
We consider the most general new physics effective Lagrangian for b --> s l+ l-. We derive the upper limit on the branching ratio for the processes B_s --> l+ l- where l=e, mu, subject to the current experimental bounds on related processes, B --> K l+ l-
Abazov +34 more
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Flux pattern transitions in the intermediate state of a type-I superconductor driven by an ac field
The intermediate state of a type-I superconductor Pb film is studied by a scanning Hall probe and scanning ac-susceptibility microscopies under static and oscillating applied magnetic fields.
J Ge +4 more
doaj +1 more source
The Fermilab Tevatron (p pbar), operating at sqrt(s)=1.96 TeV, is a rich source of B hadrons. The large acceptance in terms of rapidity and transverse momentum of the charged particle tracking system and the muon system make the upgraded Run II D0 ...
Stark, Jan
core +3 more sources
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
One of the exciting results in flavor physics in recent times is the RD/RD⁎ puzzle. The measurements of these flavor ratios performed by the B-factory experiments, BaBar and Belle, and the LHCb experiment are about 4σ away from the Standard Model ...
Ashutosh Kumar Alok +3 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Implications of the $R_K$ and $R_{K^*}$ anomalies
We discuss the implications of the recently reported $R_K$ and $R_{K^*}$ anomalies, the lepton flavor non-universality in the $B\to K\ell^+\ell^-$ and $B\to K^*\ell^+\ell^-$.
Wang, Wei, Zhao, Shuai
core +1 more source

