Results 71 to 80 of about 645,781 (307)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Measurement of branching fractions for B → χc1(2)K (K*) at Belle

open access: yes, 2006
We have measured the branching fractions for the exclusive decay modes B→χc1(2)K(K*) using a 140 fb-1 data sample collected by the Belle detector at the KEKB asymmetric-energy e +e- collider.
Blyth, S.   +201 more
core   +1 more source

First-Principles Study of the Contact Resistance at 2D Metal/2D Semiconductor Heterojunctions

open access: yesApplied Sciences, 2020
The high contact resistance at metal/two-dimensional (2D) semiconductor junctions is a major issue for the integration of 2D materials in nanoelectronic devices.
Michel Houssa   +3 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

B physics theory [PDF]

open access: yes, 1989
The status of the theoretical predictions for loop decays, strategy for precise determination of Vub and the issue of symmetric versus asymmetric machine for a B factory were discussed in the working group.
Soni, A. (Brookhaven National Lab., Upton, NY (USA). Physics Dept.)
core  

Puzzles in B physics

open access: yesPramana, 2006
6 pages, 1 figure, talk presented at the 9th Workshop on High Energy Physics Phenomenology, Bhubaneswar, Orissa, India, Jan.
openaire   +2 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Precision measurement of the B[0 over s]–[– over B][0 over s] oscillation frequency with the decay B[0 over s]→D[– over s]π[superscript +] [PDF]

open access: yes, 2013
A key ingredient to searches for physics beyond the Standard Model in B[0 over s] mixing phenomena is the measurement of the B[0 over s]–[– over B][0 over s] oscillation frequency, which is equivalent to the mass difference Δm[subscript s] of the B[0 ...
Hennessy K.   +999 more
core   +1 more source

Flux pattern transitions in the intermediate state of a type-I superconductor driven by an ac field

open access: yesNew Journal of Physics, 2013
The intermediate state of a type-I superconductor Pb film is studied by a scanning Hall probe and scanning ac-susceptibility microscopies under static and oscillating applied magnetic fields.
J Ge   +4 more
doaj   +1 more source

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