Results 71 to 80 of about 428,255 (264)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The electrocurrent microrelay modelling
Технологія та конструювання в електронній апаратурі, 2011 The design and method of electrocurrent microrelay theoretical modelling is offered. It is established, that base function in the normalized kind graphically represents a symmetric parabola.
N. I. Mukhurov +2 more
doaj
New Physics in inclusive semileptonic B decays
Journal of High Energy PhysicsWe study inclusive semileptonic $$\overline{B}\to {X }_{c}{\ell}\overline{\nu }$$ decays (ℓ = e, μ) in the presence of generic physics Beyond the Standard Model (BSM) that is heavy compared to the b-quark mass.
Alexandre Carvunis +4 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Method of stationary interference patterns reading and processing
Технологія та конструювання в електронній апаратурі, 2009 The optoelectronic reading system enables real-time acquisition and processing of interference pattern images in the Kesterse interferometer with sufficient resolution. The root-mean-square deviation of the measurement results is 0.001 mm. The total time
V. N. Ilyin +2 more
doaj
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
B PHYSICS AND CP VIOLATION [PDF]
Fundamental Interactions, 2005 These lectures provide a basic overview of topics related to the study of CP Violation in B decays. In the first lecture, I review the basics of discrete symmetries in field theories, the quantum mechanics of neutral but flavor-non-trivial mesons, and the classification of three types of CP violation.
openaire +2 more sources
Laser devices for geometric parameters measuring of three-dimensional objects
Технологія та конструювання в електронній апаратурі, 2010 The article describes measuring method and presents basic variants of multi-coordinate devices for complicated surface shape control, with distinguishing method of sounding beam forming. The constructing principle and the construction of three-coordinate
V. N. Ilyin +2 more
doaj
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source