Results 91 to 100 of about 4,112,356 (269)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

In vitro propagation of bastard balm (Melittis melissophyllum L.)

Herba Polonica, 2015
An efficient method for in vitro propagation of bastard balm by enhanced axillary shoot branching has been developed. The material to establish in vitro culture was shoot tips collected from three-year-old plants in May.
Bączek Katarzyna, Szymborska-Sandhu Izabela, Pawełczak Anna, Węglarz Zenon   +3 more
doaj   +1 more source

A-site Randomness Effect on Structural and Physical Properties of Ba-based Perovskite Manganites

, 2004
The discovery of novel structural and physical properties in the $A$-site ordered manganite $R$BaMn$_{2}$O$_{6}$ ($R$ = Y and rare earth elements) has demanded new comprehension about perovskite manganese oxides.
Akahoshi D., Aliaga H., Arima T., Hébert S., Izumi F., Kageyama H., Mahendiran R., Millange F., Motome Y., Nakajima T., Nakajima T., Nakajima T., Nakajima T., Rao C. N. R., Rodriguez-Martinez L. M., Shannon R. D., Terai T., Trukhanov S. V., Uchida M.   +18 more
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Absolute Whitehead torsion

, 2005
We refine the Whitehead torsion of a chain equivalence of finite chain complexes in an additive category $\bA$ from an element of $\widetilde{K}^{iso}_1(\bA)$ to an element of the absolute group $K_1^{iso}(\bA)$.
Andrew Korzeniewski, Ranicki, Ranicki, Ranicki, Ranicki, Ranicki   +5 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Thermodynamic properties of Ba1-xMxFe2As2 (M = La and K)

, 2008
The specific heat $C(T)$ of BaFe$_2$As$_2$ single crystal, electron-doped Ba$_{0.7}$La$_{0.3}$Fe$_2$As$_2$ and hole-doped Ba$_{0.5}$K$_{0.5}$Fe$_2$As$_2$ polycrystals were measured.
Bos J-W G, Chen G F, G Wu, H Wang, Huang Q Qiu Y Bao W Lynn J W MGreen M A Gasparovic Y C Wu T Wu G Chen X H, J K Dong, L Ding, Mu G, Ren Z A, Ren Z A, Ren Z A, S Y Li, T Wu, Wang C, Wang X F Wu T Wu G Chen H Xie Y L Ying J J Yan Y J Liu R H Chen X H, Wu G, Wu G, X F Wang, X H Chen   +18 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source