Results 31 to 40 of about 19,064 (177)

Bovine Bacillus anthracis in Cameroon [PDF]

Applied and Environmental Microbiology, 2011
ABSTRACT Bovine Bacillus anthracis isolates from Cameroon were genetically characterized. They showed a strong homogeneity, and they belong, together with strains from Chad, to cluster Aβ, which appears to be predominant in western Africa.
Pilo, Paola, Rossano, Alexandra, Bamamga, H., Abdoulkadiri, S., Perreten, Vincent, Frey, Joachim   +5 more
openaire   +4 more sources

Identification and functional analysis of class 3 lipases associated with triacylglycerol metabolism in Nannochloropsis oceanica (Eustigmatophyceae)

Journal of Phycology, EarlyView.
Abstract Microalgae accumulate triacylglycerols (TAGs) as storage lipids in response to nutrient limitation, yet the mechanisms governing TAG turnover remain incompletely understood. In the oleaginous microalga Nannochloropsis oceanica, functional studies of TAG degradation have focused on lipases containing patatin domains, whereas the roles of other ...
Masako Iwai, Koichi Hori, Tomokazu Kurita, Kumiko Okazaki, Shinichiro Maeda, Akihide Takami, Takashi Yamamoto, Atsushi Sakamoto, Hiroyuki Ohta, Mie Shimojima   +9 more
wiley   +1 more source

CRISPR-Cas9-mediated barcode insertion into Bacillus thuringiensis for surrogate tracking

Microbiology Spectrum
The use of surrogate organisms can enable researchers to safely conduct research on pathogens and in a broader set of conditions. Being able to differentiate between the surrogates used in the experiments and background contamination as well as between ...
Steven A. Higgins, Fadime Kara Murdoch, Jonathon M. Clifton, Jennifer H. Brooks, Keegan L. Fillinger, Jason K. Middleton, Bradley S. Heater   +6 more
doaj   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Antimicrobial resistance profiling and phenotypic characterization of archived clinical Bacillus paranthracis strains

Microbiology Spectrum
Bacillus paranthracis was formally defined as a species in 2017, after decades of carrying the name “emetic Bacillus cereus” based on cereulide production and clustering within the B. cereus sensu lato phylogenetic group III.
Pierre Michel, Tucker Maxson, Vasanta Chivukula, Will Overholt, Luz Karime Medina Cordoba, Stephanie Ayodele-Abiola, John McQuiston, Cari A. Beesley, Melissa Bell, Victoria Caban Figueroa, Julia Bugrysheva, Tyler Chandross-Cohen, Zachary Weiner, Laura Carroll, Jasna Kovac, David Sue   +15 more
doaj   +1 more source

Caenorhabditis elegans Predation on Bacillus anthracis: Decontamination of Spore Contaminated Soil with Germinants and Nematodes

Frontiers in Microbiology, 2018
Remediation of Bacillus anthracis-contaminated soil is challenging and approaches to reduce overall spore levels in environmentally contaminated soil or after intentional release of the infectious disease agent in a safe, low-cost manner are needed.
Bettina Schelkle, Young Choi, Leslie W. Baillie, William Richter, Fatih Buyuk, Elif Celik, Morgan Wendling, Mitat Sahin, Theresa Gallagher   +8 more
doaj   +1 more source

Quaternary structures of Streptococcus pneumoniae nucleoside diphosphate kinase: From hexamers to supramolecular assemblies

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The nucleoside diphosphate kinase (NDK) is a key enzyme that controls the balance of nucleotide pools in all living organisms. Beyond this fundamental role, NDKs exert pleiotropic effects in many cellular processes, including cell development, signal transduction, differentiation, tumor metastasis, and gene expression. The quaternary structure
Julie Kerboeuf, Paul Nouri, Frédéric Galisson, Laetitia Daury, Marie‐France Giraud, Olivier Lambert, Cédric Orelle, Lionel Ballut, Elise Kaplan, Jean‐Michel Jault, Cécile Gonzalez   +10 more
wiley   +1 more source

Underexplored Ligand‐Binding Features of FabI From Staphylococcus aureus and Escherichia coli: A Comparative Pharmacophoric Modeling and Surface Mapping Approach

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Antimicrobial resistance highlights the urgent need for novel FabI inhibitors. Using an integrated computational approach combining ConPhar pharmacophore modeling, FTMap surface mapping, and PLIP interaction profiling across experimental structures and structures from MD simulations, we identified a conserved binding core (Y156/Y157, A95) and ...
Pedro Tenório T. F. Leite, Lucas H. S. Ocarino, Gabriel C. Veríssimo, Philipe O. Fernandes, Dara Fernanda Pereira, Fernanda Kelly M. e Oliveira, Alberto Marbán‐González, José L. Medina‐Franco, Mateus Sá M. Serafim, Thales Kronenberger, Vinícius G. Maltarollo   +10 more
wiley   +1 more source

Lack of Differences in the Pharmacokinetics of Therapeutic Monoclonal Antibodies Between Japanese and Non‐Japanese Individuals

The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.
Abstract Evaluation of the pharmacokinetics (PK) of new drugs in Japanese individuals is regularly requested by the Japanese regulatory agency prior to participation in global clinical trials or for bridging approaches for regulatory approval. However, the need for PK assessments in the Japanese population may be less compelling for monoclonal ...
Paridhi Gupta, Ashish Sharma, Bernd Meibohm   +2 more
wiley   +1 more source

De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi, Alastair G. McEwan, Ulrike Kappler   +2 more
wiley   +1 more source