Results 41 to 50 of about 41,704 (219)

Comprehensive and Comparative Transcriptional Profiling of the Cell Wall Stress Response in Bacillus subtilis

Molecular Microbiology, EarlyView.
Transcriptional profiling of the primary cell envelope stress response (CESR) of Bacillus subtilis exposed to a range of cell wall‐targeting antimicrobials, combining RNAseq and high‐resolution tiling arrays. We revealed the complexity of the CESR, the contribution of extracytoplasmic function sigma factors (ECFs) and two‐component signal transduction ...
Qian Zhang, Charlène Cornilleau, Lena Friebel, Sarah Spitzner, Raphael R. Müller, Doreen Meier, Pierre Flores, Cyprien Guérin, Pierre Nicolas, Diana Wolf, Vincent Fromion, Rut Carballido‐López, Thorsten Mascher   +12 more
wiley   +1 more source

Phage therapy: An alternative to antibiotics in the age of multi-drug resistance. [PDF]

, 2017
The practice of phage therapy, which uses bacterial viruses (phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed interest in revisiting this practice.
Koskella, Britt, Lin, Derek, Lin, Henry
core   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

CRISPR-Cas9-mediated barcode insertion into Bacillus thuringiensis for surrogate tracking

Microbiology Spectrum
The use of surrogate organisms can enable researchers to safely conduct research on pathogens and in a broader set of conditions. Being able to differentiate between the surrogates used in the experiments and background contamination as well as between ...
Steven A. Higgins, Fadime Kara Murdoch, Jonathon M. Clifton, Jennifer H. Brooks, Keegan L. Fillinger, Jason K. Middleton, Bradley S. Heater   +6 more
doaj   +1 more source

Caenorhabditis elegans Predation on Bacillus anthracis: Decontamination of Spore Contaminated Soil with Germinants and Nematodes

Frontiers in Microbiology, 2018
Remediation of Bacillus anthracis-contaminated soil is challenging and approaches to reduce overall spore levels in environmentally contaminated soil or after intentional release of the infectious disease agent in a safe, low-cost manner are needed.
Bettina Schelkle, Young Choi, Leslie W. Baillie, William Richter, Fatih Buyuk, Elif Celik, Morgan Wendling, Mitat Sahin, Theresa Gallagher   +8 more
doaj   +1 more source

Evidence for diversifying selection of genetic regions of encoding putative collagen-like host-adhesive fibers in Pasteuria penetrans [PDF]

, 2019
© FEMS 2018. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided ...
Anderson, Andrews, Arohi Srivastava, Arslan, Atibalentja, Aziz, Carver, Charles, Cohan, Colson, Davies, Davies, Davies, Davies, Davies, Davies, Degnan, DePristo, Duan, Dutta, Eardly, Espanol, Felsenstein, Filée, Gascuel, Giblin-Davis, Giblin-Davis, Huynen, Jones, Kanehisa, Kaufman, Keith G Davies, Kumar, Legendre, Luijckx, Luijckx, Maddison, Mauchline, McElroy, Metchnikoff, Mohan, Mohan, Mouton, Murtagh, Noel, Philippe, R Developement Core Team, Radó-Trilla, Rajendhran, Romero, Rutherford, Sayre, Sayre, Schouls, Sharad Mohan, Sharma, Stackebrandt, Starr, Steichen, Stirling, Stirling, Sturhan, Sylvestre, Sylvestre, Tamura, Tim H Mauchline, Todd, Wiedenbeck, Woese, Yap, Zilversmit   +70 more
core   +3 more sources

A Ln‐MOF Sensor Based on Dual‐Signal Response and Logic Gating for the Ratio Fluorescence Detection of Anthrax Biomarkers

Luminescence, Volume 41, Issue 5, May 2026.
The dual‐emission MOF composite (1‐OHP/Tb@Bio‐MOF)‐based fluorescence sensing system for DPA detection involves (a) preparation of the dual‐emission MOF composite; (b) investigation of fluorescence sensing performance; (c) elucidation of the fluorescence response mechanism of 1‐OHP/Tb@Bio‐MOF to DPA; and (d) detection and application of DPA based on ...
Yuhang Zhang, Xiang Hou, Wenwen Deng, Zhixin Wang, QuTong Zheng   +4 more
wiley   +1 more source

Designed Azolopyridinium Salts Block Protective Antigen Pores In Vitro and Protect Cells from Anthrax Toxin [PDF]

, 2013
Background:Several intracellular acting bacterial protein toxins of the AB-type, which are known to enter cells by endocytosis, are shown to produce channels.
A Kronhardt, A Messmer, A Ménard, A Ménard, AA Verveen, AF Kintzer, AM Friedlander, Anika Bronnhuber, AW Artenstein, BA Krantz, C Andersen, C Bachmeyer, C Bachmeyer, C Petosa, Christoph Beitzinger, CT Bahner, D Blöcker, D Blöcker, DB Lacy, EM Nestorovich, EM Nestorovich, F Conti, F Orlik, F Orlik, F Tonello, F Tonello, F Wohnsland, G Hajós, G Timári, G Vitale, György Hajós, H Barth, H Barth, Holger Barth, I Zornetta, J Sun, J Wesche, JA Young, JC Milne, JL Elliott, K Cunningham, KA Bradley, Kerstin Duscha, L Abrami, L Abrami, L Abrami, L Abrami, L Song, Ludger Johannes, M Eigen, M Mock, Markus Huber-Lang, MJ Brown, NS Duesbery, PC Hanna, R Benz, R Benz, R Palkó, R Pellizzari, RJ Collier, RO Blaustein, RO Blaustein, Roland Benz, S Nekolla, SH Leppla, SM Bezrukov, SM Bezrukov, T Neumeyer, T Neumeyer, T Neumeyer, TC Dixon, V Escuyer, VA Karginov, VA Karginov, VA Karginov, Y Singh, Zsuzsanna Riedl   +76 more
core   +2 more sources

Halophiles and Their Biomolecules: Recent Advances and Future Applications in Biomedicine [PDF]

, 2020
The organisms thriving under extreme conditions better than any other organism living on Earth, fascinate by their hostile growing parameters, physiological features, and their production of valuable bioactive metabolites.
Amoozegar, Mohammad Ali, Corral Villa, Paulina, Ventosa Ucero, Antonio   +2 more
core   +1 more source

Repurpose an FDA‐Approved Antibody Using DARPin‐Scaffolded Bridge Protein

Chemistry–Methods, Volume 6, Issue 5, May 2026.
The cell line and scalable upstream/downstream process development needed for every new monoclonal antibody are both highly expensive and time‐consuming, significantly increasing the cost of new antibody therapeutics. By contrast, the production of many synthetic binders can be accomplished rapidly and with lower production costs.
Michael Woolley, Joshua D. Bryant, Samuel Vrana, Karuppiah Chockalingam, Zhilei Chen   +4 more
wiley   +1 more source