Results 121 to 130 of about 3,197,299 (316)

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang   +9 more
wiley   +1 more source

Assembly, growth and conductive properties of tellurium nanorods produced by Rhodococcus aetherivorans BCP1 [PDF]

open access: yes, 2018
Tellurite (TeO32-) is a hazardous and toxic oxyanion for living organisms. However, several microorganisms can bioconvert TeO32- into the less toxic form of elemental tellurium (Te0).
Anikovskiy M.   +6 more
core   +1 more source

A Facile plant mediated synthesis of silver nanoparticles using an aqueous leaf extract of Ficus hispida Linn. f. for catalytic, antioxidant and antibacterial applications

open access: yesSouth African Journal of Chemical Engineering, 2018
An aqueous leaf extract of Ficus hispida Linn. f. mediated silver nanoparticles (Ag NPs) have been prepared for reduction of 4-Nitrophenol, antioxidant and antibacterial activity against gram positive bacteria, Bacillus subtilis and gram negative ...
A.V. Ramesh   +3 more
doaj   +1 more source

Protein Language Model‐Guided Engineering of a 2,3‐Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α‐Hydroxy Ketones

open access: yesAdvanced Science, EarlyView.
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding   +5 more
wiley   +1 more source

Validation of the 3-under-2 principle of cell wall growth in Gram-positive bacteria by simulation of a simple coarse-grained model

open access: yes, 2017
The aim of this work is to propose a first coarse-grained model of Bacillus subtilis cell wall, handling explicitly the existence of multiple layers of peptidoglycans. In this first work, we aim at the validation of the recently proposed "three under two"
Carballido-López, R.   +5 more
core  

The potential of Symbiont Ba cteria in Melo melo Gastropod found in Pekalongan Waters as a source of MDR antibacterial active compound [PDF]

open access: yes, 2016
The increasing resistance of many pathogenic microorganisms against antibiotics compounds creates an alarming issue in medical world. This concern has created research opportunities in new antibiotics compounds as alternative options.
Maulidi, Zuhdi   +2 more
core  

Dynamics of the Bacillus subtilis Min System

open access: yesmBio, 2020
The molecular mechanisms that help to place the division septum in bacteria is of fundamental importance to ensure cell proliferation and maintenance of cell shape and size.
Helge Feddersen   +3 more
semanticscholar   +1 more source

Deficiency in Lipoteichoic Acid Synthesis Causes a Failure in Executing the Colony Developmental Program in Bacillus subtilis

open access: yesFrontiers in Microbiology, 2017
Colonies are an abundant form of bacterial multicellularity; however, relatively little is known about the initial stages of their construction. We have previously described that colony development of the soil bacterium Bacillus subtilis is a highly ...
Gideon Mamou   +3 more
doaj   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

open access: yesAdvanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang   +10 more
wiley   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

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