Results 141 to 150 of about 63,566 (275)

Enhanced One‐Pot Dual‐CRISPR‐Based Assay Lyophilized on a 3D‐Printed Disc for Field‐Deployable Multiplex Bacteria Detection

Advanced Science, EarlyView.
An enhanced one‐pot, helicase‐assisted recombinase polymerase amplification (hRPA)‐combined, dual‐CRISPR/uAsCas12a assay is developed and lyophilized on a 3D‐printed microfluidic disc to achieve field‐deployable multiplex bacteria detection. Abstract One‐pot CRISPR‐based detection combining recombinase polymerase amplification (RPA) enables rapid and ...
Yuqing Shen, Bo Lu, Biao Ma, Xiong Ding
wiley   +1 more source

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

Advanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera, Suneesh Thilak, Asha Patel, Prashant Nasa, Zubair Ahmed, Lorraine Jacques, William J. Scotton, Cyril Chacko, Randeep Mullhi, Ruoling Chen, Vikram Patil, Suresh Renukappa, Tonny Veenith   +12 more
wiley   +1 more source

Filamentous morphology engineering of bacteria by iron metabolism modulation through MagR expression

Synthetic and Systems Biotechnology
The morphology is the consequence of evolution and adaptation. Escherichia coli is rod-shaped bacillus with regular dimension of about 1.5 μm long and 0.5 μm wide.
Mengke Wei, Chenyang Han, Xiujuan Zhou, Tianyang Tong, Jing Zhang, Xinmiao Ji, Peng Zhang, Yanqi Zhang, Yan Liu, Xin Zhang, Tiantian Cai, Can Xie   +11 more
doaj   +1 more source

Tailoring Regioselectivity‐Controlled UDP‐Glycosyltransferase for Bidirectional Glycosylation of Tyrosol via Free Energy‐Driven Pocket Reshaping and Tunnel Engineering

Advanced Science, EarlyView.
To address inherent limitations in regioselectivity and catalytic efficiency of UDP‐glycosyltransferases, an integrated strategy combining free‐energy driven pocket reshaping and tunnel engineering is developed. This strategy enables UGTBL1 to bidirectional glycosylation of tyrosol, synthesizing salidroside or icariside D2 without extensive screening ...
Ziyu Zhang, Jingyi Chen, Zuozhi Liang, Wenming Shao, Zhen Gao, Bin Wu, Bingfang He, Gerhard Schenk   +7 more
wiley   +1 more source

Adaptation of Bacillus subtilis MreB Filaments to Osmotic Stress Depends on Influx of Potassium Ions

Microorganisms
The circumferential motion of MreB filaments plays a key role in cell shape maintenance in many bacteria. It has recently been shown that filament formation of MreB filaments in Bacillus subtilis is influenced by stress conditions. In response to osmotic
Simon Dersch, Peter L. Graumann
doaj   +1 more source

CHANGES IN THE SHAPE AND SIZE OF BACTERIUM COLI AND BACILLUS MEGATHERIUM UNDER THE INFLUENCE OF BACTERIOPHAGE—A MOTION PHOTOMICROGRAPHIC ANALYSIS OF THE MECHANISM OF LYSIS [PDF]

, 1933
Stanhope Bayne‐Jones, Leslie A. Sandholzer   +1 more
openalex   +1 more source

RiboMicrobe: An Integrated Translatome Atlas for Microorganism

Advanced Science, EarlyView.
RiboMicrobe is a comprehensive database for Ribo‐seq data from prokaryotes, featuring 891 Ribo‐seq, 369 RNA‐seq, and 62 proteome datasets from 38 species. The database not only provides various data visualization results but also includes two sORF prediction models and a suit of bioinformatics tools for comparative analysis, facilitating easy access ...
Yingshun Zhou, Jinjing Luo, Xiaoqiang Lang, Yuli Gan, Guoxian Liu, Yuling Cui, Fazhi Li, Weicong Zhu, Bing Chen, Yuanyuan Dong, Yinglin Wu, Yi Cao, Qi Liu   +12 more
wiley   +1 more source

Balancing Cell Growth and Product Synthesis for Efficient Microbial Cell Factories

Advanced Science, EarlyView.
This review presents state‐of‐the‐art metabolic engineering strategies to balance microbial cell growth and product synthesis in biorefineries. It surveys pathway engineering, dynamic genetic circuits, orthogonal control systems, synthetic microbial consortia, and fermentation optimization, alongside integrative modeling approaches.
Linxia Liu, Dongqin Ding, Huiying Wang, Xinyi Ren, Sang Yup Lee, Dawei Zhang   +5 more
wiley   +1 more source

Comparative Evaluation of Chemical Reduction Methods by Ethanol and Bacillus licheniformis on The Physical Properties, Stability and Coating of Nanoparticles

Medical Laboratory Journal, 2016
Background and Objectives: Size of silver nanoparticles synthesized by ethanol and Bacillus lichenioformisis 20 nm and 15 nm, respectively. Nanoparticles can be used in treatment of several diseases.
Shima Doostmohammadi, Babak Kheirkhah, Seyed Mohammad Reza Khoshroo   +2 more
doaj  

Bacillus subtilis MreB paralogues have different filament architectures and lead to shape remodelling of a heterologous cell system [PDF]

, 2010
Hervé Joël Defeu Soufo, Peter L. Graumann   +1 more
openalex   +1 more source